SCHEMBL6978615

SCHEMBL6978615

c1cc(C2CNCCO2)nnn1

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.41
DRD3 P35462 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5756194 0.81 DRD2 (0.44) DRD2DRD3
SCHEMBL20038176 0.74
SCHEMBL28834644 0.74
SCHEMBL2325497 0.74
SCHEMBL9902553 0.73 DRD2 (0.40) DRD2DRD3
SCHEMBL9733118 0.73 ALDH1A1 (0.36)
SCHEMBL8216855 0.73
SCHEMBL1521725 0.73 DRD2 (0.40) DRD2DRD3
SCHEMBL25173291 0.72 DRD2 (0.49) DRD2DRD3
SCHEMBL22325 0.72 DRD2 (0.45) DRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1185528-A4 INHIBITORS OF IL-12 PRODUCTION SHIONOGI BIORES CORP (US) 2003-03-26 EP disclosed
US-6384032-B1 INTERLEUKIN INHIBITORS SHIONOGI BIORESEARCH CORP. 2002-05-07 US disclosed
EP-1185528-A1 INHIBITORS OF IL-12 PRODUCTION Shionogi Bioresearch Corporation (US) 2002-03-13 EP disclosed
WO-2000078757-A1 INHIBITORS OF IL-12 PRODUCTION SHIONOGI BIORESEARCH CORP. (US) 2000-12-28 WO disclosed