Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 7/20 | 0.70 |
| ▸ | EGFR | P00533 | 5/20 | 0.70 |
| ▸ | HPGDS | O60760 | 1/20 | 0.66 |
| ▸ | KIT | P10721 | 10/20 | 0.65 |
| ▸ | CSF1R | P07333 | 9/20 | 0.65 |
| ▸ | ABL1 | P00519 | 5/20 | 0.60 |
| ▸ | BCR | P11274 | 5/20 | 0.60 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.60 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.60 |
| ▸ | LCK | P06239 | 2/20 | 0.60 |
| ▸ | FYN | P06241 | 2/20 | 0.60 |
| ▸ | LYN | P07948 | 2/20 | 0.60 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.60 |
| ▸ | FGR | P09769 | 2/20 | 0.60 |
| ▸ | SRC | P12931 | 2/20 | 0.60 |
| ▸ | NQO2 | P16083 | 2/20 | 0.60 |
| ▸ | EPHA8 | P29322 | 2/20 | 0.60 |
| ▸ | ABL2 | P42684 | 2/20 | 0.60 |
| ▸ | FRK | P42685 | 2/20 | 0.60 |
| ▸ | BLK | P51451 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6782706 | 0.89 | HPGDS (0.75) | BRAFEGFRHPGDSKITCSF1R | |
| SCHEMBL6780729 | 0.86 | HPGDS (0.67) | BRAFEGFRHPGDSKITCSF1R | |
| SCHEMBL31721202 | 0.86 | HPGDS (0.69) | BRAFEGFRHPGDSKITCSF1R | |
| SCHEMBL6967943 | 0.86 | HPGDS (0.67) | BRAFEGFRHPGDSKITCSF1R | |
| SCHEMBL6973506 | 0.86 | HPGDS (0.64) | BRAFEGFRHPGDSKITCSF1R | |
| SCHEMBL7677867 | 0.85 | HPGDS (0.66) | BRAFEGFRHPGDSKITCSF1R | |
| SCHEMBL6966564 | 0.84 | HPGDS (0.65) | BRAFHPGDSKITCSF1RMAPT | |
| SCHEMBL31721283 | 0.84 | DDR1 (0.60) | BRAFEGFRHPGDSKITCSF1R | |
| SCHEMBL7681667 | 0.84 | HPGDS (0.63) | BRAFEGFRHPGDSKITCSF1R | |
| SCHEMBL6239405 | 0.84 | ABL1 (0.86) | BRAFEGFRKITCSF1RABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115707-B1 | BENZAMIDE DERIVATIVES AND THER USE AS CYTOKINE INHIBITORS | ASTRAZENECA AB (SE) | 2003-11-12 | — | — | EP | disclosed |
| US-6455520-B1 | TUMOR NECROSIS FACTOR AND INTERLEUKIN INHIBITORS; ANTIINFLAMMATORY AGENTS, ANTIALLERGENS; BONE DISORDERS | ASTRA ZENECA AB (SE) | 2002-09-24 | — | — | US | disclosed |