Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 3/20 | 0.46 |
| ▸ | PDK3 | Q15120 | 3/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958782 | 0.91 | IDO1 (0.45) | POLBL3MBTL1PDK1PDK2PDK3 | |
| SCHEMBL7956609 | 0.91 | NR3C1 (0.44) | PDK1PDK2PDK3PDK4TP53 | |
| SCHEMBL6980414 | 0.91 | TP53 (0.44) | TP53KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL7958428 | 0.90 | MEN1 (0.46) | TP53KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL6981025 | 0.89 | MEN1 (0.57) | TP53KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL7080783 | 0.88 | POLB (0.48) | POLBL3MBTL1PDK1PDK2PDK3 | |
| Hydrochloric Acid SCHEMBL6980241 | 0.87 | POLB (0.48) | POLBL3MBTL1PDK1PDK2PDK3 | |
| SCHEMBL7960198 | 0.87 | MEN1 (0.43) | POLBTP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL7958965 | 0.86 | IDO1 (0.45) | POLBPDK1PDK2PDK3PDK4 | |
| SCHEMBL6986538 | 0.85 | TP53 (0.49) | PDK1PDK2PDK3PDK4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |