Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TXK | P42681 | 1/20 | 0.41 |
| ▸ | ITK | Q08881 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958965 | 0.91 | IDO1 (0.45) | NR3C1TP53ITKPDK1PDK2 | |
| SCHEMBL6978699 | 0.91 | POLB (0.48) | NR3C1PGRTP53ALDH1A1TSHR | |
| SCHEMBL6982704 | 0.87 | ITGB3 (0.44) | TP53ALDH1A1TSHRMAPTSMN1; SMN2 | |
| SCHEMBL6985998 | 0.86 | NR3C1 (0.47) | NR3C1TP53ALDH1A1TSHRMEN1 | |
| SCHEMBL7958782 | 0.86 | IDO1 (0.45) | NR3C1TP53ITKPDK1PDK2 | |
| SCHEMBL6984728 | 0.85 | TP53 (0.44) | NR3C1PGRTP53ALDH1A1TSHR | |
| SCHEMBL7958945 | 0.84 | PDK1 (0.41) | NR3C1TP53ALDH1A1TSHRMEN1 | |
| SCHEMBL6977634 | 0.84 | NR3C1 (0.53) | NR3C1TP53ALDH1A1TSHRMEN1 | |
| SCHEMBL7958691 | 0.84 | ALDH1A1 (0.46) | NR3C1TP53ALDH1A1TSHRMEN1 | |
| SCHEMBL6986006 | 0.84 | NR3C1 (0.46) | NR3C1TP53ALDH1A1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |