Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318068 | 0.91 | ALDH1A1 (0.73) | ALDH1A1PKMLMNAMAOBKMT2A | |
| SCHEMBL27516416 | 0.89 | ALDH1A1 (0.71) | ALDH1A1PKMLMNAMAOBKMT2A | |
| SCHEMBL9177530 | 0.79 | ALDH1A1 (0.71) | ALDH1A1PKMLMNAMAOBKMT2A | |
| SCHEMBL3822991 | 0.77 | ALDH1A1 (1.00) | ALDH1A1PKMLMNAMAOBKMT2A | |
| SCHEMBL10565349 | 0.76 | ALDH1A1 (0.67) | ALDH1A1PKMLMNAMAOBKMT2A | |
| SCHEMBL6979345 | 0.76 | ALDH1A1 (0.58) | ALDH1A1LMNAMAOBKMT2AMAOA | |
| SCHEMBL6978794 | 0.76 | ALDH1A1 (0.71) | ALDH1A1PKMLMNAMAOBKMT2A | |
| SCHEMBL11197686 | 0.75 | ALDH1A1 (0.76) | ALDH1A1PKMLMNAMAOBKMT2A | |
| SCHEMBL6211890 | 0.74 | ALDH1A1 (0.80) | ALDH1A1PKMLMNAMAOBKMT2A | |
| SCHEMBL4109285 | 0.74 | ALDH1A1 (0.69) | ALDH1A1PKMLMNAMAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228058-A4 | BENZOPYRANYL GUANIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HANNONG CHEMICAL CO LTD (KR) | 2003-02-12 | — | — | EP | disclosed |
| EP-1228058-A1 | BENZOPYRANYL GUANIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dongbu Hannong Chemical Co., Ltd. (KR) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001029023-A1 | BENZOPYRANYL GUANIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2001-04-26 | — | — | WO | disclosed |