SCHEMBL6979018

SCHEMBL6979018

[N]C1CCCC(Cc2ccccc2)N1

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.54
GBA1 P04062 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6976719 0.96 POLB (0.59) POLBGBA1
SCHEMBL6965239 0.89 POLB (0.49) POLBGBA1
SCHEMBL6976167 0.81
SCHEMBL6981221 0.81 POLB (0.45) POLB
SCHEMBL6976968 0.79 POLB (0.40) POLB
SCHEMBL5530485 0.78 POLB (0.57) POLBGBA1
SCHEMBL6975226 0.78 SLC18A3 (0.43) POLB
SCHEMBL6978104 0.77 SLC18A3 (0.42) POLB
SCHEMBL6978425 0.76 CHRNB2 (0.42) POLB
SCHEMBL6968881 0.76 LTA4H (0.40) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0821674-B1 CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS SEARLE & CO (US) 2003-08-06 EP claimed