Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257934 | 0.84 | ITGB3 (0.42) | ITGB3ITGA2BKLK5 | |
| SCHEMBL9260554 | 0.84 | ITGB3 (0.42) | ITGB3ITGA2BKLK5 | |
| SCHEMBL6979088 | 0.84 | ITGB3 (0.39) | ITGB3ITGA2BKLK5 | |
| SCHEMBL6979118 | 0.83 | ALDH1A1 (0.33) | — | |
| SCHEMBL9425678 | 0.81 | ITGB3 (0.42) | ITGB3ITGA2BKLK5 | |
| SCHEMBL9264739 | 0.78 | ITGB3 (0.42) | ITGB3ITGA2BKLK5 | |
| SCHEMBL9426346 | 0.77 | F2 (0.43) | ITGB3ITGA2BKLK5 | |
| SCHEMBL7352320 | 0.75 | ITGB3 (0.45) | ITGB3ITGA2BKLK5 | |
| SCHEMBL9425991 | 0.72 | KLK5 (0.40) | KLK5 | |
| SCHEMBL6972937 | 0.72 | PARP1 (0.58) | KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630366-B1 | SUBSTITUTED HETEROCYCLIC DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | SEARLE & CO (US) | 2003-01-02 | — | — | EP | disclosed |
| US-5378727-A | ADMINISTERING TO MAMMALS | G. D. SEARLE & CO. (US) | 1995-01-03 | — | — | US | disclosed |
| US-5254573-A | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| EP-0539343-A1 | Substituted heterocyclic derivatives useful as platelet aggregation inhibitors | MONSANTO COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |