Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | HPN | P05981 | 1/20 | 0.36 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.36 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976476 | 0.92 | F2 (0.36) | F2F10HPNHGFACST14 | |
| SCHEMBL6976548 | 0.91 | MAOA (0.46) | NPC1RAB9ASMN1; SMN2MAOAMAOB | |
| SCHEMBL6976777 | 0.88 | MAOB (0.43) | MAOAMAOB | |
| SCHEMBL6976622 | 0.88 | SMYD3 (0.41) | NPC1RAB9AF2F10HPN | |
| SCHEMBL6976837 | 0.87 | F2 (0.37) | F2F10HPNHGFACST14 | |
| SCHEMBL6972556 | 0.86 | — | — | |
| SCHEMBL6975948 | 0.86 | F2 (0.39) | F2F10HPNHGFACST14 | |
| SCHEMBL27507310 | 0.84 | NPC1 (0.36) | NPC1RAB9AALDH1A1HSP90AA1F2 | |
| SCHEMBL7081704 | 0.80 | F2 (0.45) | F2F10HPNHGFACST14 | |
| SCHEMBL6979285 | 0.77 | F2 (0.46) | F2F10HPNHGFACST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833839-B1 | PEPTIDYL HETEROCYCLES USEFUL IN THE TREATMENT OF THROMBIN RELATED DISORDERS | ORTHO PHARMA CORP (US) | 2003-01-08 | — | — | EP | claimed |