Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 5/20 | 0.41 |
| ▸ | GRM7 | Q14831 | 2/20 | 0.41 |
| ▸ | FPR1 | P21462 | 2/20 | 0.41 |
| ▸ | FPR2 | P25090 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.40 |
| ▸ | OXTR | P30559 | 2/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.40 |
| ▸ | HAT1 | O14929 | 3/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984354 | 0.89 | PTGER4 (0.49) | TP53EP300GRM7HDAC1HDAC8 | |
| SCHEMBL6977738 | 0.83 | TP53 (0.51) | TP53HDAC1HDAC8HDAC6IDO1 | |
| SCHEMBL7964635 | 0.82 | TP53 (0.47) | TP53EP300GRM7HDAC1HDAC8 | |
| SCHEMBL6984356 | 0.81 | SMN1; SMN2 (0.53) | TP53EP300HDAC1HDAC8HDAC6 | |
| SCHEMBL6977395 | 0.80 | TP53 (0.46) | TP53HDAC1HDAC8HDAC6AVPR2 | |
| SCHEMBL6978698 | 0.79 | POLB (0.49) | TP53HDAC1HDAC8HDAC6 | |
| SCHEMBL6979412 | 0.79 | NAMPT (0.49) | TP53HDAC1HDAC8HDAC6 | |
| SCHEMBL7085009 | 0.79 | TP53 (0.49) | TP53EP300FPR1FPR2HDAC1 | |
| SCHEMBL6985246 | 0.78 | TP53 (0.51) | TP53HDAC1HDAC8HDAC6IDO1 | |
| SCHEMBL7958428 | 0.78 | MEN1 (0.46) | TP53HDAC1HDAC8HDAC6AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |