Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983535 | 0.87 | TP53 (0.44) | POLBTP53MMP1LMNASMN1; SMN2 | |
| SCHEMBL7948557 | 0.86 | TP53 (0.45) | POLBTP53MMP1SMN1; SMN2HDAC1 | |
| SCHEMBL6977738 | 0.85 | TP53 (0.51) | POLBTP53SMN1; SMN2HDAC1HDAC8 | |
| SCHEMBL6984356 | 0.83 | SMN1; SMN2 (0.53) | TP53SMN1; SMN2HDAC1HDAC8HDAC6 | |
| SCHEMBL6985377 | 0.82 | RAB9A (0.62) | POLBTP53LMNAHTTSMN1; SMN2 | |
| SCHEMBL6984354 | 0.82 | PTGER4 (0.49) | TP53LMNAHDAC1HDAC8HDAC6 | |
| SCHEMBL6985246 | 0.82 | TP53 (0.51) | TP53LMNASMN1; SMN2HDAC1HDAC8 | |
| SCHEMBL6977395 | 0.82 | TP53 (0.46) | TP53LMNAHTTSMN1; SMN2HDAC1 | |
| SCHEMBL6979412 | 0.81 | NAMPT (0.49) | TP53SMN1; SMN2HDAC1HDAC8HDAC6 | |
| SCHEMBL7085009 | 0.80 | TP53 (0.49) | TP53SMN1; SMN2HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |