Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 2/20 | 0.37 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8861592 | 0.89 | CA2 (0.45) | NPC1RAB9AKDM4ETDP1HKDC1 | |
| SCHEMBL30675321 | 0.87 | NPC1 (0.58) | NPC1RAB9AKDM4ETDP1HKDC1 | |
| SCHEMBL28723880 | 0.85 | MEN1 (0.46) | NPC1RAB9AKDM4ETDP1HKDC1 | |
| SCHEMBL2098094 | 0.75 | NPC1 (0.53) | NPC1RAB9AKDM4ETDP1HKDC1 | |
| SCHEMBL30675320 | 0.75 | NPC1 (0.53) | NPC1RAB9AKDM4ETDP1HKDC1 | |
| SCHEMBL928266 | 0.75 | NPC1 (0.47) | NPC1RAB9AKDM4ETDP1L3MBTL1 | |
| SCHEMBL29967146 | 0.75 | NPC1 (0.47) | NPC1RAB9AKDM4ETDP1L3MBTL1 | |
| SCHEMBL31609687 | 0.75 | ALDH1A1 (0.50) | NPC1RAB9ATDP1L3MBTL1ALDH1A1 | |
| SCHEMBL26276500 | 0.75 | ALDH1A1 (0.41) | NPC1RAB9AKDM4ETDP1HKDC1 | |
| SCHEMBL30917341 | 0.74 | NPC1 (0.74) | NPC1RAB9AKDM4ETDP1HKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177194-B1 | 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS | BASF AG (DE) | 2003-09-17 | — | — | EP | disclosed |
| EP-1177179-A1 | BENZOHETERO CYCLYLCYCLO HEXENONES AND THEIR USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-06 | — | — | EP | disclosed |
| EP-1177194-A1 | 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000068228-A1 | 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-16 | — | — | WO | disclosed |
| WO-2000068210-A1 | BENZOHETERO CYCLYLCYCLO HEXENONES AND THEIR USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-16 | — | — | WO | disclosed |