Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 4/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | ATP4A | P20648 | 2/20 | 0.47 |
| ▸ | ATP4B | P51164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6984061 | 0.99 | CYP2C9 (0.55) | CYP2C9CYP2C19CYP19A1CYP2D6CYP3A4 | |
| SCHEMBL6982852 | 0.98 | CYP2C9 (0.54) | CYP2C9CYP2C19CYP19A1CYP2D6CYP3A4 | |
| SCHEMBL6981113 | 0.97 | CYP2C9 (0.53) | CYP2C9CYP2C19CYP19A1CYP2D6CYP3A4 | |
| Hydrochloric Acid SCHEMBL6981899 | 0.97 | CYP2C9 (0.53) | CYP2C9CYP2C19CYP19A1CYP2D6CYP3A4 | |
| Hydrochloric Acid SCHEMBL6979794 | 0.96 | CYP2C9 (0.52) | CYP2C9CYP2C19CYP19A1CYP2D6CYP3A4 | |
| SCHEMBL6987016 | 0.95 | CYP19A1 (0.50) | CYP2C9CYP2C19CYP19A1CYP2D6CYP3A4 | |
| Hydrochloric Acid SCHEMBL6981896 | 0.94 | CYP19A1 (0.49) | CYP2C9CYP2C19CYP19A1CYP2D6CYP3A4 | |
| SCHEMBL6985635 | 0.90 | MAPT (0.56) | CYP2C9CYP2C19CYP19A1CYP2D6CYP3A4 | |
| Hydrochloric Acid SCHEMBL6987032 | 0.89 | MAPT (0.54) | CYP2C9CYP2C19CYP19A1CYP2D6CYP3A4 | |
| SCHEMBL6984109 | 0.87 | CHRNB2 (0.52) | CYP2C9CYP2C19CYP19A1CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | DAIICHI PHARMACEUTICAL CO. LTD. | 2003-07-10 | — | — | US | disclosed |
| EP-1283209-A1 | NOVEL BENZOTHIOPHENE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | CYP17A1, CYP21A2, HSD17B1 | CYP2C9 100/4885CYP2C19 65/4885CYP19A1 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.