Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984820 | 0.89 | HTR6 (0.61) | HTR6SMN1; SMN2LMNAKMT2AKDM4E | |
| SCHEMBL31681377 | 0.82 | EIF2AK2 (0.54) | HTR6SMN1; SMN2LMNAALDH1A1THRB | |
| SCHEMBL12375664 | 0.81 | GFER (0.47) | SMN1; SMN2LMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL7982796 | 0.81 | HTR6 (0.68) | HTR6SMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL6984749 | 0.81 | MLNR (0.50) | KMT2AKDM4EALDH1A1BRD4HPGD | |
| SCHEMBL10959038 | 0.79 | PKM (0.58) | HTR6SMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL5871138 | 0.78 | SMN1; SMN2 (0.69) | HTR6SMN1; SMN2LMNAKMT2AKDM4E | |
| SCHEMBL2229992 | 0.78 | HTR2C (0.61) | SMN1; SMN2KMT2AALDH1A1BRD4HTR2C | |
| Hydrochloric Acid SCHEMBL10957321 | 0.78 | PKM (0.57) | HTR6SMN1; SMN2LMNAKMT2AALDH1A1 | |
| SCHEMBL19329330 | 0.77 | HDAC3 (0.46) | SMN1; SMN2LMNAKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |