Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
| ▸ | DRD1 | P21728 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 9/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983932 | 0.91 | CHRM2 (0.43) | CHRM2ADRA2ACHRM1DRD1SLC6A2 | |
| SCHEMBL6984910 | 0.87 | KCNA3 (0.44) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL6976601 | 0.78 | KCNA3 (0.41) | — | |
| Hydrochloric Acid SCHEMBL6984801 | 0.77 | SMN1; SMN2 (0.43) | CHRM2ADRA2ACHRM1DRD1SLC6A2 | |
| Hydrochloric Acid SCHEMBL6985676 | 0.76 | SMN1; SMN2 (0.42) | SLC6A2SLC6A3OPRM1CYP2D6MAPK1 | |
| Hydrochloric Acid SCHEMBL6985053 | 0.75 | SMN1; SMN2 (0.41) | SLC6A2SLC6A3OPRM1CYP2D6MAPK1 | |
| Hydrochloric Acid SCHEMBL6984864 | 0.75 | OPRL1 (0.38) | OPRM1CYP2D6OPRK1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6985438 | 0.75 | SMN1; SMN2 (0.41) | SLC6A2SLC6A3OPRM1CYP2D6MAPK1 | |
| Hydrochloric Acid SCHEMBL6983999 | 0.75 | SMN1; SMN2 (0.41) | SLC6A2SLC6A3OPRM1CYP2D6MAPK1 | |
| SCHEMBL6980208 | 0.74 | CARM1 (0.43) | OPRM1HRH3BCHESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |