Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 8/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 8/20 | 0.43 |
| ▸ | PRMT8 | Q9NR22 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 6/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985090 | 0.89 | OPRM1 (0.36) | CARM1PRMT6PRMT8SIGMAR1TMEM97 | |
| SCHEMBL6979708 | 0.85 | PRMT6 (0.43) | CARM1PRMT6PRMT8SIGMAR1TMEM97 | |
| Hydrochloric Acid SCHEMBL6985853 | 0.82 | DRD2 (0.40) | CARM1PRMT6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6979051 | 0.81 | LMNA (0.41) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6982195 | 0.77 | SIGMAR1 (0.45) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6986246 | 0.75 | ADRA1D (0.46) | — | |
| Hydrochloric Acid SCHEMBL6981605 | 0.72 | MEN1 (0.41) | BCHE | |
| Hydrochloric Acid SCHEMBL6985676 | 0.72 | SMN1; SMN2 (0.42) | SIGMAR1OPRM1 | |
| Hydrochloric Acid SCHEMBL6984562 | 0.72 | SIGMAR1 (0.43) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6986381 | 0.70 | KDM4E (0.41) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |