Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | DRD1 | P21728 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 7/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.37 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979555 | 0.91 | CHRM2 (0.44) | CHRM2ADRA2ACHRM1DRD1SLC6A2 | |
| SCHEMBL6976601 | 0.87 | KCNA3 (0.41) | — | |
| SCHEMBL6980208 | 0.83 | CARM1 (0.43) | OPRM1HRH3BCHESIGMAR1 | |
| Hydrochloric Acid SCHEMBL6984801 | 0.83 | SMN1; SMN2 (0.43) | CHRM2ADRA2ACHRM1DRD1SLC6A2 | |
| SCHEMBL6981567 | 0.82 | DRD2 (0.40) | HTR1ACYP2D6DRD2ADRA1BSIGMAR1 | |
| SCHEMBL6976120 | 0.82 | GAA (0.32) | — | |
| Hydrochloric Acid SCHEMBL6985676 | 0.81 | SMN1; SMN2 (0.42) | SLC6A2SLC6A3OPRM1CYP2D6MAPK1 | |
| Hydrochloric Acid SCHEMBL6985853 | 0.81 | DRD2 (0.40) | HTR1ACYP2D6DRD2ADRA1BSIGMAR1 | |
| Hydrochloric Acid SCHEMBL6985053 | 0.80 | SMN1; SMN2 (0.41) | SLC6A2SLC6A3OPRM1CYP2D6MAPK1 | |
| SCHEMBL6985090 | 0.80 | OPRM1 (0.36) | OPRM1HRH3DRD2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |