Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974503 | 0.87 | HRH3 (0.44) | EPHX1POLBMAPTLMNAGAA | |
| SCHEMBL11469205 | 0.78 | POLB (0.58) | EPHX1POLBMAPTLMNAGAA | |
| SCHEMBL10376287 | 0.78 | POLB (0.53) | EPHX1POLBMAPTLMNAGAA | |
| SCHEMBL6976968 | 0.77 | POLB (0.40) | POLBLMNATRPA1 | |
| SCHEMBL8139586 | 0.77 | KMT2A (0.44) | EPHX1POLBMAPTLMNAGAA | |
| SCHEMBL6976719 | 0.77 | POLB (0.59) | POLB | |
| SCHEMBL6972927 | 0.76 | SMN1; SMN2 (0.43) | EPHX1POLBMAPTLMNAGAA | |
| SCHEMBL17542138 | 0.75 | TBXA2R (0.49) | POLBLOXL2ALDH1A1KMT2ATBXA2R | |
| SCHEMBL17542137 | 0.75 | TBXA2R (0.49) | POLBLOXL2ALDH1A1KMT2ATBXA2R | |
| SCHEMBL6447825 | 0.75 | LMNA (0.52) | EPHX1POLBMAPTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | claimed |