Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 18/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6979544 | 0.83 | CRHR1 (0.67) | CRHR1 | |
| SCHEMBL6980405 | 0.83 | CRHR1 (0.67) | CRHR1 | |
| Hydrochloric Acid SCHEMBL6985057 | 0.79 | CRHR1 (0.62) | CRHR1 | |
| SCHEMBL7684973 | 0.78 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL6986689 | 0.78 | CRHR1 (0.81) | CRHR1 | |
| SCHEMBL7687005 | 0.76 | CRHR1 (0.77) | CRHR1 | |
| Hydrochloric Acid SCHEMBL8451419 | 0.74 | CRHR1 (0.70) | CRHR1 | |
| SCHEMBL7678011 | 0.73 | CRHR1 (0.81) | CRHR1 | |
| SCHEMBL6984017 | 0.73 | CRHR1 (0.75) | CRHR1 | |
| Hydrochloric Acid SCHEMBL6986992 | 0.73 | CRHR1 (0.68) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976745-B1 | 4-TETRAHYDROPYRIDYLPYRIMIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-08-13 | — | — | EP | disclosed |
| US-6187781-B1 | CORTICOTROPIN RELEASING FACTOR RECEPTOR ANTAGONISTS; ALZHEIMER*S, HUNTINGTON, AND PARKINSON DISEASE; ANTIDEPRESSANTS, ANXIOLYTIC AGENTS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2001-02-13 | — | — | US | disclosed |
| EP-0976745-A1 | 4-TETRAHYDROPYRIDYLPYRIMIDINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2000-02-02 | — | — | EP | disclosed |