Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1272573 | 0.77 | CYP1A2 (0.50) | CYP1A2RAB9AKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL6986645 | 0.76 | CYP1A2 (0.43) | CYP1A2RAB9AKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL6606473 | 0.75 | CYP1A2 (0.42) | CYP1A2RAB9AKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL27578438 | 0.75 | TRPV1 (0.44) | CYP1A2KMT2AHIF1AEPAS1PDE10A | |
| SCHEMBL1272570 | 0.74 | CYP1A2 (0.50) | CYP1A2RAB9AKDM4EHIF1AEPAS1 | |
| SCHEMBL6987795 | 0.73 | CYP1A2 (0.43) | CYP1A2RAB9AKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL6981602 | 0.73 | CYP1A2 (0.38) | CYP1A2RAB9AKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL6607278 | 0.73 | CYP1A2 (0.42) | CYP1A2RAB9AKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL6607276 | 0.73 | CYP1A2 (0.42) | CYP1A2RAB9AKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL6606289 | 0.73 | CYP1A2 (0.42) | CYP1A2RAB9AKDM4EKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289980-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090100-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-11-29 | — | — | WO | disclosed |