Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | FCER2 | P06734 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6606473 | 0.88 | CYP1A2 (0.42) | CYP1A2HIF1AEPAS1HPGDMGAM | |
| SCHEMBL6987795 | 0.86 | CYP1A2 (0.43) | CYP1A2HIF1AEPAS1PTGESALOX5 | |
| SCHEMBL6981602 | 0.83 | CYP1A2 (0.38) | CYP1A2HIF1AEPAS1PTGESALOX5 | |
| SCHEMBL6606289 | 0.83 | CYP1A2 (0.42) | CYP1A2HIF1AEPAS1MMP9MMP1 | |
| SCHEMBL6665570 | 0.82 | KDM4E (0.40) | CYP1A2HIF1AEPAS1PDE10AMMP9 | |
| SCHEMBL6608479 | 0.81 | MMP2 (0.45) | CYP1A2HIF1AEPAS1PDE10AMMP9 | |
| SCHEMBL6608483 | 0.81 | MMP2 (0.45) | CYP1A2HIF1AEPAS1PDE10AMMP9 | |
| SCHEMBL6607278 | 0.80 | CYP1A2 (0.42) | CYP1A2HIF1AEPAS1PTGESALOX5 | |
| Hydrochloric Acid SCHEMBL6612642 | 0.80 | CYP1A2 (0.42) | CYP1A2HIF1AEPAS1PDE10AMMP9 | |
| SCHEMBL6607276 | 0.80 | CYP1A2 (0.42) | CYP1A2HIF1AEPAS1PTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289980-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM PLC (GB) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090100-A1 | BICYCLYL OR HETEROBICYCLYLMETHANESULFONYLAMINO-SUBSTITUTED N-HYDROXYFORMAMIDES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-11-29 | — | — | WO | disclosed |