Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 11/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 11/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ACP1 | P24666 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2210476 | 0.86 | DYRK1A (0.56) | DYRK1ARAB9AMAPTNPC1LMNA | |
| SCHEMBL11224458 | 0.85 | DYRK1A (0.55) | DYRK1ARAB9AMAPTNPC1LMNA | |
| SCHEMBL3093869 | 0.85 | RAB9A (0.57) | DYRK1ARAB9AMAPTNPC1LMNA | |
| SCHEMBL13466474 | 0.83 | RAB9A (0.63) | DYRK1ARAB9AMAPTNPC1ALDH1A1 | |
| SCHEMBL28919888 | 0.81 | DYRK1A (0.61) | DYRK1ARAB9AMAPTNPC1LMNA | |
| SCHEMBL6983750 | 0.81 | DYRK1A (0.61) | DYRK1ARAB9AMAPTNPC1LMNA | |
| SCHEMBL22849991 | 0.80 | SMN1; SMN2 (0.59) | DYRK1ARAB9AMAPTNPC1LMNA | |
| SCHEMBL17038164 | 0.80 | PTPN1 (0.59) | DYRK1ARAB9AMAPTNPC1ACP1 | |
| SCHEMBL22849990 | 0.79 | DYRK1A (0.63) | DYRK1ARAB9AMAPTNPC1LMNA | |
| SCHEMBL28919891 | 0.79 | GAA (0.55) | DYRK1ARAB9AMAPTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115504942-A | Synthesis method of alkyl or acyl substituted benzothiazole derivative | 汕头大学 | 2022-12-23 | — | — | CN | disclosed |
| EP-1006114-B1 | PYRAZOLE DERIVATIVES AND COX INHIBITORS CONTAINING THEM | GRELAN PHARMACEUTICAL CO (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-6136831-A | ANTIINFLAMMATORY AGENTS, GASTROINTESTINAL AGENTS, ENZYME INHIBITORS | GRELAN PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-1006114-A1 | PYRAZOLE DERIVATIVES AND COX INHIBITORS CONTAINING THEM | Grelan Pharmaceutical Co., Ltd. (JP) | 2000-06-07 | — | — | EP | disclosed |