Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 8/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ACP1 | P24666 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.49 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980043 | 0.86 | DYRK1A (0.60) | DYRK1ARAB9AMAPTNPC1LMNA | |
| SCHEMBL3093869 | 0.85 | RAB9A (0.57) | DYRK1ARAB9AMAPTNPC1LMNA | |
| SCHEMBL11224458 | 0.85 | DYRK1A (0.55) | DYRK1ARAB9AMAPTNPC1LMNA | |
| SCHEMBL4352378 | 0.82 | HSD17B1 (0.67) | DYRK1AMAPTMAOBHSD17B1HSD17B2 | |
| SCHEMBL17038138 | 0.82 | SMN1; SMN2 (0.58) | RAB9AMAPTNPC1LMNAMAOB | |
| SCHEMBL8402901 | 0.82 | HSD17B1 (0.66) | DYRK1ARAB9AMAPTNPC1LMNA | |
| SCHEMBL18365000 | 0.80 | MAPT (0.50) | RAB9AMAPTNPC1LMNAMAOB | |
| SCHEMBL17038164 | 0.80 | PTPN1 (0.59) | DYRK1ARAB9AMAPTNPC1ACP1 | |
| SCHEMBL4137369 | 0.79 | PPARA (0.57) | DYRK1ARAB9AMAPTNPC1HSD17B1 | |
| SCHEMBL3641915 | 0.79 | PPARA (0.57) | DYRK1ARAB9AMAPTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250171438-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. | 2025-05-29 | — | — | US | disclosed |
| WO-2023164237-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. (US) | 2023-08-31 | — | — | WO | disclosed |
| WO-2023164237-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | AGIOS PHARMACEUTICALS, INC. (US) | 2023-08-31 | — | — | WO | disclosed |
| CN-112209930-B | Itratheophylline derivative, and preparation method and application thereof | 山东新华制药股份有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-112209930-A | Istradefylline derivative and preparation method and application thereof | 山东新华制药股份有限公司 | 2021-01-12 | — | — | CN | disclosed |
| EP-1952918-B1 | METHOD FOR PRODUCING METAL PARTICLE DISPERSION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM | TOYO INK MFG CO (JP) | 2013-05-22 | — | — | EP | disclosed |
| US-8440110-B2 | Method for producing metal particle dispersion, conductive ink using metal particle dispersion produced by such method, and conductive coating film | TOYO INK MFG CO., LTD. (JP) | 2013-05-14 | — | — | US | disclosed |
| US-20110175040-A1 | METHOD FOR PRODUCING METAL PARTICLE DISPRESION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM | TOYO INK MFG CO., LTD. (JP) | 2011-07-21 | — | — | US | disclosed |
| US-7981327-B2 | Method for producing metal particle dispersion, conductive ink using metal particle dispersion produced by such method, and conductive coating film | TOYO INK MFG. CO. LTD. (JP) | 2011-07-19 | — | — | US | disclosed |
| US-20090258202-A1 | Method for Producing Metal Particle Dispersion, Conductive Ink Using Metal Particle Dispersion Produced by Such Method, and Conductive Coating Film | GVP GESELLSCHAFT ZUR VERMARKTUNG DER PORENBRENNERTECHNIK MBH (DE) | 2009-10-15 | — | — | US | disclosed |
| EP-1952918-A1 | METHOD FOR PRODUCING METAL PARTICLE DISPERSION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM | Toyo Ink Mfg. Co., Ltd (JP) | 2008-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250171438-A1 | COMPOUNDS AND METHODS USEFUL FOR STABILIZING PHENYLALANINE HYDROXYLASE MUTATIONS | PAH, KDM8, PHF8 | DYRK1A 1814/4885RAB9A 1335/4885MAPT 2359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.