Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.63 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6971109 | 0.86 | PTGS2 (0.65) | PTGS2ABCG2KDM4EALDH1A1CYP3A4 | |
| SCHEMBL6977806 | 0.85 | PTGS2 (0.67) | PTGS2MAPK14PTGS1PLA2G2APLA2G4A | |
| SCHEMBL6977093 | 0.85 | PTGS2 (0.85) | PTGS2MAPK14PTGS1PLA2G2APLA2G4A | |
| SCHEMBL6974845 | 0.85 | PTGS2 (0.72) | PTGS2MAPK14PTGS1ABCG2PLA2G2A | |
| SCHEMBL6973940 | 0.83 | PTGS2 (0.69) | PTGS2MAPK14PTGS1PLA2G2APLA2G4A | |
| SCHEMBL6977512 | 0.82 | PTGS2 (0.65) | PTGS2MAPK14PTGS1PLA2G2APLA2G4A | |
| SCHEMBL6970224 | 0.82 | PTGS2 (0.67) | PTGS2MAPK14PTGS1PLA2G2APLA2G4A | |
| SCHEMBL6978875 | 0.82 | PTGS2 (0.67) | PTGS2MAPK14PTGS1PLA2G2APLA2G4A | |
| SCHEMBL6979358 | 0.82 | PTGS2 (0.67) | PTGS2MAPK14PTGS1PLA2G2APLA2G4A | |
| SCHEMBL6979278 | 0.81 | MAPK14 (0.71) | PTGS2MAPK14PTGS1PLA2G2APLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105384-B1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-03-26 | — | — | EP | claimed |
| US-6340694-B1 | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORPORATION (KR) | 2002-01-22 | — | — | US | claimed |
| CN-1323301-A | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORP (KR) | 2001-11-21 | — | — | CN | claimed |
| EP-1105384-B1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-03-26 | — | — | EP | disclosed |
| US-6340694-B1 | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORPORATION (KR) | 2002-01-22 | — | — | US | disclosed |
| CN-1323301-A | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORP (KR) | 2001-11-21 | — | — | CN | disclosed |
| EP-1105384-A1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000010993-A1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2000-03-02 | — | — | WO | disclosed |