Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 8/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978523 | 0.89 | PPARG (0.51) | MAOBCA2PPARGRARGRXRA | |
| SCHEMBL9570601 | 0.78 | MAOB (0.61) | MAOBCA2KMT2APPARGRXRA | |
| SCHEMBL1520824 | 0.78 | MAOB (1.00) | MAOBCA2KMT2APPARGMAPT | |
| SCHEMBL9570681 | 0.74 | MAOB (0.69) | MAOBCA2KMT2APPARGMAPT | |
| SCHEMBL9570622 | 0.74 | MAOB (0.83) | MAOBCA2KMT2APPARGMAPT | |
| SCHEMBL6977977 | 0.73 | PPARG (0.66) | PPARGRARGRXRAFFAR1 | |
| SCHEMBL9375245 | 0.73 | PPARG (0.60) | MAOBCA2KMT2APPARGMAPT | |
| SCHEMBL9375186 | 0.71 | PPARG (0.61) | MAOBCA2KMT2APPARGMAPT | |
| SCHEMBL12521889 | 0.71 | MAOB (0.74) | MAOBCA2PPARGFFAR1 | |
| SCHEMBL9372631 | 0.70 | PPARG (0.60) | MAOBCA2KMT2APPARGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801063-B1 | Thiazolidinedione derivatives having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | REDDYS LAB LTD DR (IN) | 2003-01-15 | — | — | EP | disclosed |
| US-5925656-A | CONTAINING A 2,4-DIOXOTRIAZOLIDINE RING | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-07-20 | — | — | US | disclosed |
| EP-0801063-A1 | Thiazolidinedione derivatives having antidiabetic, hypolipidaemic antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1997-10-15 | — | — | EP | disclosed |