Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9570680 | 0.86 | MAPT (0.60) | MAOBMAPTPPARGALDH1A1NPSR1 | |
| SCHEMBL9570616 | 0.85 | MAPT (0.61) | MAOBMAPTPPARGALDH1A1NPSR1 | |
| SCHEMBL9570681 | 0.84 | MAOB (0.69) | MAOBMAPTCA2PPARGALDH1A1 | |
| SCHEMBL9570622 | 0.84 | MAOB (0.83) | MAOBMAPTCA2PPARGALDH1A1 | |
| SCHEMBL9617824 | 0.81 | MAPT (0.53) | MAOBMAPTPPARGALDH1A1NPSR1 | |
| SCHEMBL9570557 | 0.80 | HRH3 (0.58) | MAPTPPARGALDH1A1HRH3KMT2A | |
| SCHEMBL6980240 | 0.78 | MAOB (0.60) | MAOBMAPTCA2PPARGKMT2A | |
| SCHEMBL9570573 | 0.78 | HRH3 (0.60) | MAPTPPARGALDH1A1HRH3KMT2A | |
| SCHEMBL1520158 | 0.77 | MAOB (0.71) | MAOBMAPTCA2PPARGALDH1A1 | |
| SCHEMBL5213619 | 0.77 | MAOB (0.71) | MAOBMAPTCA2PPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533933-A1 | BISHETEROCYCLIC COMPOUND | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |