Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976719 | 0.75 | POLB (0.59) | POLB | |
| SCHEMBL1429568 | 0.75 | POLB (0.50) | GLAHTTNPSR1KMT2APOLB | |
| SCHEMBL6969853 | 0.72 | GLA (0.41) | GLAHTTNPSR1KMT2APOLB | |
| SCHEMBL6980292 | 0.72 | GLA (0.41) | GLAHTTNPSR1KMT2APOLB | |
| SCHEMBL6979018 | 0.71 | POLB (0.54) | POLB | |
| SCHEMBL6976712 | 0.70 | USP2 (0.43) | HTTNPSR1KMT2APOLBLMNA | |
| SCHEMBL6976968 | 0.69 | POLB (0.40) | POLBLMNA | |
| SCHEMBL6978425 | 0.69 | CHRNB2 (0.42) | KMT2APOLB | |
| SCHEMBL8550523 | 0.67 | GLA (0.36) | GLAHTTNPSR1 | |
| SCHEMBL6981221 | 0.67 | POLB (0.45) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | claimed |