Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977732 | 0.85 | HSD17B10 (0.40) | HRH3MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL6981221 | 0.76 | POLB (0.45) | — | |
| SCHEMBL13393831 | 0.76 | HRH3 (0.44) | HRH3TAAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL6980335 | 0.74 | HRH3 (0.38) | HRH3TAAR1MEN1KMT2AHPGD | |
| SCHEMBL6976836 | 0.74 | GAA (0.40) | HRH3 | |
| Hydrochloric Acid SCHEMBL6976887 | 0.73 | HRH3 (0.37) | HRH3TAAR1MEN1KMT2AHPGD | |
| SCHEMBL29064511 | 0.73 | HPGD (0.56) | HRH3TAAR1MEN1KMT2AHPGD | |
| SCHEMBL6980218 | 0.72 | CHRM2 (0.36) | ALDH1A1 | |
| SCHEMBL6978953 | 0.72 | NR1H4 (0.36) | — | |
| SCHEMBL6975226 | 0.71 | SLC18A3 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | claimed |