Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981221 | 0.83 | POLB (0.45) | — | |
| SCHEMBL22652854 | 0.79 | HRH3 (0.55) | HRH3 | |
| SCHEMBL6967476 | 0.77 | HRH3 (0.43) | HRH3 | |
| SCHEMBL6978540 | 0.76 | HRH3 (0.41) | RAB9ASMN1; SMN2HRH3 | |
| SCHEMBL6978953 | 0.75 | NR1H4 (0.36) | — | |
| SCHEMBL6975226 | 0.74 | SLC18A3 (0.43) | — | |
| SCHEMBL6976834 | 0.74 | GAA (0.37) | GAAMMP13RAB9ASMN1; SMN2CYP19A1 | |
| SCHEMBL6980039 | 0.74 | CYP19A1 (0.43) | GAAMMP13RAB9ASMN1; SMN2CYP19A1 | |
| SCHEMBL6980339 | 0.74 | HRH3 (0.40) | HRH3 | |
| SCHEMBL13393935 | 0.73 | HRH3 (0.43) | CYP19A1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | claimed |