Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 5/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7085291 | 0.92 | MAPT (0.37) | MAPTRAB9AGAAMAOAMAOB | |
| SCHEMBL6975335 | 0.90 | KCNH2 (0.39) | MAPTRAB9AGAAMAOAMAOB | |
| SCHEMBL6969675 | 0.89 | MEN1 (0.38) | MAPTMAOBMCHR1KCNH2MEN1 | |
| SCHEMBL6967803 | 0.88 | KCNH2 (0.43) | MAPTSMN1; SMN2MCHR1KCNH2MEN1 | |
| SCHEMBL8486214 | 0.85 | PSEN1 (0.39) | MAPTMEN1KMT2ATDP1PSEN1 | |
| SCHEMBL6973597 | 0.84 | PSEN1 (0.39) | MAPTMEN1KMT2ATDP1PSEN1 | |
| SCHEMBL6967404 | 0.84 | PSEN1 (0.37) | MAPTMEN1KMT2ATDP1PSEN1 | |
| SCHEMBL6968210 | 0.84 | PSEN1 (0.37) | MAPTMEN1KMT2ATDP1PSEN1 | |
| SCHEMBL6967865 | 0.83 | HPGD (0.51) | MAOAMAOBMEN1KMT2APPARG | |
| SCHEMBL6967873 | 0.83 | HPGD (0.51) | MAOAMAOBMEN1KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801063-B1 | Thiazolidinedione derivatives having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | REDDYS LAB LTD DR (IN) | 2003-01-15 | — | — | EP | disclosed |