Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980496 | 0.88 | SMN1; SMN2 (0.33) | SMN1; SMN2MAPTALDH1A1CYP2D6S1PR3 | |
| SCHEMBL6989143 | 0.86 | EPHX2 (0.30) | — | |
| SCHEMBL12797912 | 0.84 | MAPT (0.37) | SMN1; SMN2MAPTALDH1A1CYP2D6S1PR3 | |
| SCHEMBL12270902 | 0.81 | SMN1; SMN2 (0.32) | SMN1; SMN2MAPTALDH1A1CYP2D6S1PR3 | |
| SCHEMBL6980483 | 0.81 | CHRNB2 (0.36) | SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6979577 | 0.81 | SMN1; SMN2 (0.33) | SMN1; SMN2MAPTALDH1A1CYP2D6 | |
| SCHEMBL6977306 | 0.80 | MEN1 (0.40) | SMN1; SMN2NFE2L2MAPTALDH1A1CYP2D6 | |
| SCHEMBL6977343 | 0.80 | SMN1; SMN2 (0.32) | SMN1; SMN2MAPTALDH1A1CYP2D6 | |
| SCHEMBL12797914 | 0.79 | GAA (0.40) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL6981129 | 0.79 | MEN1 (0.39) | SMN1; SMN2S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183268-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES, LLC. (US) | 2012-05-22 | — | — | US | disclosed |
| US-8017788-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES LLC (US) | 2011-09-13 | — | — | US | disclosed |
| US-8017788-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES LLC (US) | 2011-09-13 | — | — | US | disclosed |
| US-20100173950-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | CORTEVA AGRISCIENCE LLC | 2010-07-08 | — | — | US | disclosed |
| US-20100173962-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2010-07-08 | — | — | US | disclosed |
| US-20100173950-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | CORTEVA AGRISCIENCE LLC | 2010-07-08 | — | — | US | disclosed |
| US-20100173962-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2010-07-08 | — | — | US | disclosed |
| US-20100168172-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | CORTEVA AGRISCIENCE LLC | 2010-07-01 | — | — | US | disclosed |
| US-7705156-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES LLC (US) | 2010-04-27 | — | — | US | disclosed |
| US-7705156-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES LLC (US) | 2010-04-27 | — | — | US | disclosed |
| US-20080108666-A1 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | CORTEVA AGRISCIENCE LLC | 2008-05-08 | — | — | US | disclosed |
| US-20080108666-A1 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | CORTEVA AGRISCIENCE LLC | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108666-A1 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | STS, DDT, TST | SMN1; SMN2 515/4885NFE2L2 1724/4885MAPT 4701/4885 |
| US-20100173962-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | STS, DDT, TST | SMN1; SMN2 515/4885NFE2L2 1724/4885MAPT 4701/4885 |
| US-20100173950-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | STS, DDT, TST | SMN1; SMN2 515/4885NFE2L2 1724/4885MAPT 4701/4885 |
| US-20100168172-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | STS, DDT, TST | SMN1; SMN2 515/4885NFE2L2 1724/4885MAPT 4701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.