⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methoxymethane SCHEMBL9700240 | 0.88 | RECQL (0.39) | — | |
| Ether SCHEMBL9560126 | 0.82 | GAA (0.35) | — | |
| SCHEMBL3305420 | 0.81 | ALDH1A1 (0.41) | — | |
| SCHEMBL8995940 | 0.79 | ALDH1A1 (0.44) | — | |
| SCHEMBL1156656 | 0.79 | ALDH1A1 (0.41) | — | |
| SCHEMBL9559963 | 0.78 | EPHX2 (0.36) | — | |
| SCHEMBL3051875 | 0.78 | — | — | |
| SCHEMBL6980549 | 0.76 | — | — | |
| SCHEMBL27628786 | 0.76 | ALDH1A1 (0.31) | — | |
| SCHEMBL3685052 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200324027-A1 | IMMOBILISED BIOLOGICAL ENTITIES | GORE & ASS (US) | 2020-10-15 | — | — | US | disclosed |
| EP-1534291-B1 | 2-(PHENYLTHIOMETHYL)- MORPHOLINE DERIVATIVES FOR USE AS SELECTIVE NOREPINEPHRINE REUPTAKE INHIBITORS | LILLY CO ELI (US) | 2008-11-12 | — | — | EP | disclosed |
| EP-0985671-B1 | PYRIDOCARBAZOLE DERIVATIVES HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-6476021-B1 | Compounds having cGMP-PDE inhibitory effect | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| US-6197768-B1 | THERAPY, PREVENTION ISCHEMIC HEART DISEASE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-1048666-A1 | NOVEL COMPOUNDS HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | EP | disclosed |
| EP-0992240-A1 | THERAPEUTIC AGENT FOR ERECTION FAILURE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-12 | — | — | EP | disclosed |
| EP-0985671-A1 | PYRIDOCARBAZOLE DERIVATIVES HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-6018046-A | SELECTIVE ACTION IN INHIBITING CYCLIC GMP-PHOSPHODIESTERASE (CGMP-PDE); PHARMACEUTICALS FOR TREATING DISEASES AGAINST WHICH THE INHIBITORY ACTION IS EFFECTIVE, SUCH AS PULMONARY HYPERTENSION | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
| EP-0340254-A1 | PACKAGE AND WRAPPER | Daniel, Peter Gottfried (DE) | 1989-11-08 | — | — | EP | disclosed |
| EP-0311571-A1 | Packaging and packet | SANDOZ AG (CH) | 1989-04-12 | — | — | EP | disclosed |
| US-4587246-A | CARDIOTONIC | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-05-06 | — | — | US | disclosed |
| US-4503054-A | VASODILATORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-03-05 | — | — | US | disclosed |
| EP-0002518-B1 | CONDENSATION PRODUCT OF EPSILON-CAPROLACTAM, FORMALDEHYDE AND FORMAMIDE, AMINOPLAST MODIFIED BY THIS CONDENSATION PRODUCT AND PROCESS FOR THE PREPARATION OF THE AMINOPLAST | CASSELLA Aktiengesellschaft (DE) | 1981-11-04 | — | — | EP | disclosed |
| EP-0002518-A2 | Condensation product of epsilon-caprolactam, formaldehyde and formamide, aminoplast modified by this condensation product and process for the preparation of the aminoplast | CASSELLA Aktiengesellschaft (DE) | 1979-06-27 | — | — | EP | disclosed |