SCHEMBL6981075

SCHEMBL6981075

O=[PH2]N=Cc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
ALDH1A1 P00352 3/20 0.43
CYP2A6 P11509 1/20 0.43
NOX1 Q9Y5S8 1/20 0.43
GRIN2D O15399 2/20 0.41
GRIN3B O60391 2/20 0.41
GRIN1 Q05586 2/20 0.41
GRIN2A Q12879 2/20 0.41
GRIN2B Q13224 2/20 0.41
GRIN2C Q14957 2/20 0.41
GRIN3A Q8TCU5 2/20 0.41
TAAR1 Q96RJ0 1/20 0.41
CA2 P00918 3/20 0.41
CA1 P00915 2/20 0.41
PLA2G7 Q13093 1/20 0.41
MAPT P10636 2/20 0.39
GAA P10253 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1017488 0.72
SCHEMBL1017490 0.72
SCHEMBL1119267 0.71 LMNA (1.00) LMNAL3MBTL1MEN1KMT2AALDH1A1
SCHEMBL1130162 0.71 LMNA (1.00) LMNAL3MBTL1MEN1KMT2AALDH1A1
SCHEMBL396304 0.71 LMNA (1.00) LMNAL3MBTL1MEN1KMT2AALDH1A1
SCHEMBL10341826 0.68 LMNA (0.70) LMNAL3MBTL1MEN1KMT2AALDH1A1
SCHEMBL8597431 0.68 LMNA (0.55) LMNAL3MBTL1MEN1KMT2AALDH1A1
SCHEMBL2751035 0.68 LMNA (0.55) LMNAL3MBTL1MEN1KMT2AALDH1A1
SCHEMBL24715428 0.67 LMNA (0.60) LMNAL3MBTL1MEN1KMT2AALDH1A1
Benzaldehyde Oxime SCHEMBL266504 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0724569-B1 PROCESS FOR THE PREPARATION OF AN OXIRANE, AZIRIDINE OR CYCLOPROPANE AVECIA LTD (GB) 2003-03-12 EP disclosed