Sugi Predict

Sugi Predict / Compounds / SCHEMBL396304

SCHEMBL396304

SCHEMBL396304

C(=NN=Cc1ccccc1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 1.00
▸ L3MBTL1 Q9Y468 1/20 1.00
▸ GRIN2D O15399 2/20 0.61
▸ GRIN3B O60391 2/20 0.61
▸ GRIN1 Q05586 2/20 0.61
▸ GRIN2A Q12879 2/20 0.61
▸ GRIN2B Q13224 2/20 0.61
▸ GRIN2C Q14957 2/20 0.61
▸ GRIN3A Q8TCU5 2/20 0.61
▸ TAAR1 Q96RJ0 1/20 0.61
▸ ALDH1A1 P00352 4/20 0.52
▸ NPC1 O15118 3/20 0.52
▸ RAB9A P51151 2/20 0.52
▸ MAPT P10636 2/20 0.52
▸ SMN1; SMN2 Q16637 1/20 0.52
▸ MEN1 O00255 3/20 0.52
▸ KMT2A Q03164 3/20 0.52
▸ CHRM5 P08912 3/20 0.50
▸ NOX1 Q9Y5S8 1/20 0.50
▸ CYP1A2 P05177 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1119267 1.00 LMNA (1.00) LMNAL3MBTL1GRIN2DGRIN3BGRIN1
SCHEMBL1130162 1.00 LMNA (1.00) LMNAL3MBTL1GRIN2DGRIN3BGRIN1
SCHEMBL14002472 0.87 LMNA (0.75) LMNAL3MBTL1GRIN2DGRIN3BGRIN1
SCHEMBL20266347 0.84 MAPT (0.81) LMNAL3MBTL1GRIN2DGRIN3BGRIN1
SCHEMBL20378738 0.84 MAPT (0.81) LMNAL3MBTL1GRIN2DGRIN3BGRIN1
SCHEMBL11688356 0.84 LMNA (0.71) LMNAL3MBTL1GRIN2DGRIN3BGRIN1
SCHEMBL5341729 0.83 LMNA (0.70) LMNAL3MBTL1GRIN2DGRIN3BGRIN1
SCHEMBL14885337 0.83 LMNA (0.70) LMNAL3MBTL1GRIN2DGRIN3BGRIN1
SCHEMBL5808345 0.83 LMNA (0.70) LMNAL3MBTL1GRIN2DGRIN3BGRIN1
SCHEMBL10341826 0.83 LMNA (0.70) LMNAL3MBTL1GRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228854-A1 POLYMER AND THERMAL INTERFACE MATERIAL INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2024-07-11 — — US claimed
EP-3091967-A1 COMPOSITIONS FOR USE IN THE TREATMENT OF ULCERATIVE COLITIS Sigmoid Pharma Limited (IE) 2016-11-16 — — EP claimed
CN-106132400-A Composition for treating ulcerative colitis 希格默伊德药业有限公司 2016-11-16 — — CN claimed
WO-2015104414-A1 COMPOSITIONS FOR USE IN THE TREATMENT OF ULCERATIVE COLITIS SIGMOID PHARMA LIMITED (IE) 2015-07-16 — — WO claimed
CN-103275161-B 3-hydroxyl cholest-6-keto aromatic aldehyde azine steroidal compound, synthetic method of steroidal compound and application of steroidal compound in preparation of anti-tumour drug UNIV GUANGXI TEACHERS EDUCATION 2015-04-15 — — CN claimed
US-20130231308-A1 USE OF AMINOSALICYLATES IN DIARRHOEA-PREDOMINENT IRRITABLE BOWEL SYNDROME SHORTIS NICOLAS PETER (AU) 2013-09-05 — — US claimed
CN-101282708-B External preparation for skin containing a phosphorlated saccharide EZAKI GLICO CO 2013-03-20 — — CN claimed
US-8168227-B2 Modified powder and cosmetic composition using the same SHISEIDO CO., LTD. (JP) 2012-05-01 — — US claimed
EP-2361620-A1 Use of aminosalicylates in diarrhoea-predominant irritable bowel syndrome PHARMATEL (R&D) PTY LIMITED as Trustee for the PHARMATEL (R & D) TRUST (AU) 2011-08-31 — — EP claimed
CN-102014926-A Methods and kits for the treatment of inflammatory bowel disorder conditions PROCTER & GAMBLE 2011-04-13 — — CN claimed
WO-1998045108-A1 TRANSPARENT ARTICLE WITH RADIAL REFRACTIVE INDEX GRADIENT AND PROCESS FOR ITS MANUFACTURE ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 1998-10-15 — — WO claimed
WO-1998008362-A1 PRINTABLE COMPOSITIONS, AND THEIR APPLICATION TO DIELECTRIC SURFACES USED IN THE MANUFACTURE OF PRINTED CIRCUIT BOARDS CRAIG HUGH P (GB) 1998-02-26 — — WO claimed
US-5519014-A Treatment of non-inflammatory and non-infectious bowel disorders CENTRE FOR DIGESTIVE DISEASES PTY LTD. (AU) 1996-05-21 — — US claimed
US-5332784-A Conjugated diene, vinylaromatic copolymer ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1994-07-26 — — US claimed
EP-0554291-A4 TREATMENT OF NON-INFLAMMATORY AND NON-INFECTIOUS BOWEL DISORDERS — 1993-09-08 — — EP claimed
EP-0554291-A1 TREATMENT OF NON-INFLAMMATORY AND NON-INFECTIOUS BOWEL DISORDERS BORODY, Thomas Julius (AU) 1993-08-11 — — EP claimed
WO-1992006690-A1 TREATMENT OF NON-INFLAMMATORY AND NON-INFECTIOUS BOWEL DISORDERS BORODY THOMAS J (AU) 1992-04-30 — — WO claimed
US-5000937-A Transparent cosmetic composition that reflects infrared radiation and its use for protecting the human epidermis against infrared radiation L'OREAL (FR) 1991-03-19 — — US claimed
US-4015014-A Method for the use of aryl azines as anthelmintics THE DOW CHEMICAL COMPANY (US) 1977-03-29 — — US claimed
US-3934003-A Cosmetic composition containing an ethoxylated glyceride mixture CHEMISCHE WERKE WITTEN GMBH (DT) 1976-01-20 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130231308-A1 USE OF AMINOSALICYLATES IN DIARRHOEA-PREDOMINENT IRRITABLE BOWEL SYNDROME SLC10A2, SI, ABAT LMNA 4798/4885L3MBTL1 4420/4885GRIN2D 28/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.