Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 17/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | NFKBIA | P25963 | 3/20 | 0.73 |
| ▸ | RELA | Q04206 | 2/20 | 0.73 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.68 |
| ▸ | G6PD | P11413 | 1/20 | 0.68 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.68 |
| ▸ | METAP2 | P50579 | 1/20 | 0.68 |
| ▸ | METAP1 | P53582 | 1/20 | 0.68 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.68 |
| ▸ | MDM4 | O15151 | 1/20 | 0.67 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.67 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1507919 | 0.88 | SLC40A1 (0.76) | SLC40A1TDP1MEN1KMT2ANFKBIA | |
| SCHEMBL30854809 | 0.88 | SLC40A1 (0.76) | SLC40A1TDP1MEN1KMT2ANFKBIA | |
| SCHEMBL30925451 | 0.84 | SLC40A1 (1.00) | SLC40A1TDP1MEN1KMT2ANFKBIA | |
| SCHEMBL22116968 | 0.84 | SLC40A1 (0.71) | SLC40A1TDP1MEN1KMT2ANFKBIA | |
| SCHEMBL460773 | 0.84 | SLC40A1 (1.00) | SLC40A1TDP1MEN1KMT2ANFKBIA | |
| SCHEMBL11973367 | 0.84 | SLC40A1 (1.00) | SLC40A1TDP1MEN1KMT2ANFKBIA | |
| SCHEMBL18434290 | 0.84 | SLC40A1 (0.76) | SLC40A1TDP1MEN1KMT2ANFKBIA | |
| SCHEMBL11973197 | 0.84 | SLC40A1 (1.00) | SLC40A1TDP1MEN1KMT2ANFKBIA | |
| SCHEMBL31676665 | 0.84 | SLC40A1 (1.00) | SLC40A1TDP1MEN1KMT2ANFKBIA | |
| SCHEMBL13485955 | 0.84 | SLC40A1 (0.67) | SLC40A1TDP1MEN1KMT2ANFKBIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6528187-B1 | Luminescence element comprising pair of electrodes having formed therebetween plurality of organic compound thin film layers comprising electron-transporting layer which comprises specified compound | FUJI PHOTO FILM CO., LTD. (JP) | 2003-03-04 | — | — | US | disclosed |
| EP-0991624-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000371-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-01-07 | — | — | WO | disclosed |