Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8155541 | 0.99 | ACHE (0.61) | ACHESMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL6962578 | 0.90 | ACHE (0.58) | ACHESMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL6983031 | 0.89 | ACHE (0.64) | ACHESMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL6984091 | 0.89 | ACHE (0.60) | ACHESMN1; SMN2KDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL8150680 | 0.88 | ACHE (0.58) | ACHESMN1; SMN2KDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL8147530 | 0.88 | ACHE (0.60) | ACHESMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL6976891 | 0.87 | ACHE (0.61) | ACHESMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL6977695 | 0.86 | ACHE (0.56) | ACHESMN1; SMN2KDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL8150216 | 0.86 | ACHE (0.61) | ACHESMN1; SMN2KDM4EALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL6973524 | 0.85 | ACHE (0.60) | ACHESMN1; SMN2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934938-B1 | SUBSTITUTED BENZOYLAMINOTHIAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 2003-01-15 | — | — | EP | disclosed |