Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8147530 | 0.99 | ACHE (0.60) | ACHESMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL6961470 | 0.91 | ACHE (0.57) | ACHESMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL6985028 | 0.90 | ACHE (0.56) | ACHESMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL6981293 | 0.89 | ACHE (0.61) | ACHESMN1; SMN2NPC1RAB9AHPGD | |
| Hydrochloric Acid SCHEMBL8155541 | 0.88 | ACHE (0.61) | ACHESMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL6962160 | 0.87 | ACHE (0.55) | ACHESMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL6984499 | 0.87 | ACHE (0.55) | ACHESMN1; SMN2NPC1RAB9AHPGD | |
| Oxalic Acid SCHEMBL8141022 | 0.85 | ACHE (0.53) | ACHESMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL6975566 | 0.85 | ACHE (0.58) | ACHESMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL6981511 | 0.83 | ACHE (0.57) | ACHENPC1RAB9AKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934938-B1 | SUBSTITUTED BENZOYLAMINOTHIAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME | ZERIA PHARM CO LTD (JP) | 2003-01-15 | — | — | EP | disclosed |