Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 19/20 | 1.00 |
| ▸ | DRD2 | P14416 | 14/20 | 1.00 |
| ▸ | DRD4 | P21917 | 2/20 | 0.75 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985375 | 0.92 | DRD3 (1.00) | DRD3DRD2DRD4 | |
| SCHEMBL6986108 | 0.92 | DRD3 (1.00) | DRD3DRD2 | |
| SCHEMBL6985952 | 0.87 | DRD3 (1.00) | DRD3DRD2DRD4SIGMAR1 | |
| SCHEMBL6978822 | 0.86 | DRD3 (1.00) | DRD3DRD2DRD4SIGMAR1 | |
| SCHEMBL6982595 | 0.85 | DRD3 (1.00) | DRD3DRD2DRD4SIGMAR1 | |
| SCHEMBL8528789 | 0.84 | DRD3 (0.79) | DRD3DRD2DRD4SIGMAR1 | |
| SCHEMBL6984294 | 0.83 | DRD3 (1.00) | DRD3DRD2DRD4 | |
| SCHEMBL6984226 | 0.83 | DRD3 (1.00) | DRD3DRD2DRD4 | |
| SCHEMBL6985049 | 0.83 | DRD3 (1.00) | DRD3DRD2DRD4SIGMAR1 | |
| SCHEMBL8286906 | 0.82 | DRD2 (1.00) | DRD3DRD2DRD4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751939-B9 | NAPHTHYLAMIDES AS CENTRAL NERVOUS SYSTEM AGENTS | WARNER LAMBERT CO (US) | 2003-01-02 | — | — | EP | claimed |
| EP-0751939-B1 | NAPHTHYLAMIDES AS CENTRAL NERVOUS SYSTEM AGENTS | WARNER LAMBERT CO (US) | 2002-06-12 | — | — | EP | claimed |
| WO-1995025727-A1 | NAPHTHYLAMIDES AS CENTRAL NERVOUS SYSTEM AGENTS | WARNER-LAMBERT COMPANY (US) | 1995-09-28 | — | — | WO | claimed |
| US-5395835-A | Antipsychotic agents | WARNER-LAMBERT COMPANY (US) | 1995-03-07 | — | — | US | claimed |
| EP-0751939-B9 | NAPHTHYLAMIDES AS CENTRAL NERVOUS SYSTEM AGENTS | WARNER LAMBERT CO (US) | 2003-01-02 | — | — | EP | disclosed |
| EP-0751939-B1 | NAPHTHYLAMIDES AS CENTRAL NERVOUS SYSTEM AGENTS | WARNER LAMBERT CO (US) | 2002-06-12 | — | — | EP | disclosed |
| EP-0751939-A1 | NAPHTHYLAMIDES AS CENTRAL NERVOUS SYSTEM AGENTS | WARNER-LAMBERT COMPANY (US) | 1997-01-08 | — | — | EP | disclosed |
| WO-1995025727-A1 | NAPHTHYLAMIDES AS CENTRAL NERVOUS SYSTEM AGENTS | WARNER-LAMBERT COMPANY (US) | 1995-09-28 | — | — | WO | disclosed |
| US-5395835-A | Antipsychotic agents | WARNER-LAMBERT COMPANY (US) | 1995-03-07 | — | — | US | disclosed |