Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 18/20 | 0.79 |
| ▸ | DRD2 | P14416 | 10/20 | 0.79 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.74 |
| ▸ | DRD4 | P21917 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8525948 | 0.90 | DRD3 (0.78) | DRD3DRD2SIGMAR1 | |
| SCHEMBL6986108 | 0.89 | DRD3 (1.00) | DRD3DRD2 | |
| SCHEMBL6985952 | 0.86 | DRD3 (1.00) | DRD3DRD2SIGMAR1DRD4 | |
| SCHEMBL6984294 | 0.86 | DRD3 (1.00) | DRD3DRD2DRD4 | |
| SCHEMBL6984226 | 0.86 | DRD3 (1.00) | DRD3DRD2DRD4 | |
| SCHEMBL8285981 | 0.86 | SIGMAR1 (1.00) | DRD3DRD2SIGMAR1DRD4 | |
| SCHEMBL6985375 | 0.85 | DRD3 (1.00) | DRD3DRD2DRD4 | |
| SCHEMBL6981463 | 0.84 | DRD3 (1.00) | DRD3DRD2SIGMAR1DRD4 | |
| SCHEMBL6984893 | 0.84 | DRD3 (1.00) | DRD3DRD2DRD4 | |
| SCHEMBL6985049 | 0.84 | DRD3 (1.00) | DRD3DRD2SIGMAR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539281-B1 | Naphthamides, process for their preparation and their application in the therapeutical field | INST NAT SANTE RECH MED (FR) | 1998-12-30 | — | — | EP | disclosed |
| EP-0539281-A1 | New naphthamides, process for their preparation and their application in the therapeutical field | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1993-04-28 | — | — | EP | disclosed |