Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 13/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985425 | 0.90 | NR3C1 (0.52) | NR3C1 | |
| SCHEMBL6979710 | 0.88 | NR3C1 (0.41) | NR3C1BRD4CREBBPTRIM24 | |
| SCHEMBL7088163 | 0.86 | PARP1 (0.37) | NR3C1CASP1 | |
| SCHEMBL7085092 | 0.85 | ALDH1A1 (0.39) | NR3C1CASP1 | |
| Hydrochloric Acid SCHEMBL6977752 | 0.85 | F2 (0.49) | NR3C1TSHRBRD4CREBBPSLC16A3 | |
| SCHEMBL6982493 | 0.84 | NR3C1 (0.50) | NR3C1TSHRBRD4CREBBPTRIM24 | |
| SCHEMBL6978185 | 0.83 | ALDH1A1 (0.51) | NR3C1BRD4CREBBP | |
| SCHEMBL6976718 | 0.83 | NR3C1 (0.42) | NR3C1TSHRBRD4CREBBPSLC16A3 | |
| SCHEMBL6981262 | 0.83 | NR3C1 (0.53) | NR3C1 | |
| SCHEMBL7089638 | 0.82 | PARP1 (0.36) | NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |
| EP-0991624-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1999000371-A1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-01-07 | — | — | WO | disclosed |