Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 3/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981686 | 1.00 | SLC6A9 (0.36) | SLC6A9GBA1MCHR1TACR1SOS1 | |
| SCHEMBL8473770 | 1.00 | SLC6A9 (0.36) | SLC6A9GBA1MCHR1TACR1SOS1 | |
| SCHEMBL8507434 | 0.89 | SLC6A2 (0.41) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6979250 | 0.89 | SLC6A2 (0.41) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6979254 | 0.89 | SLC6A2 (0.41) | OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL8508323 | 0.87 | OPRL1 (0.42) | MCHR1MAPK1OPRM1OPRD1OPRK1 | |
| SCHEMBL6974169 | 0.87 | OPRL1 (0.42) | MCHR1MAPK1OPRM1OPRD1OPRK1 | |
| SCHEMBL6974165 | 0.87 | OPRL1 (0.42) | MCHR1MAPK1OPRM1OPRD1OPRK1 | |
| SCHEMBL7872456 | 0.87 | OPRL1 (0.42) | MCHR1MAPK1OPRM1OPRD1OPRK1 | |
| SCHEMBL6979034 | 0.87 | OPRL1 (0.42) | MCHR1MAPK1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817772-B1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER (US) | 2003-01-29 | — | — | EP | disclosed |
| US-6110947-A | AN ANALGESIC AGENT FOR TREATING STROKE, ABDOMINAL PAIN; AS ANTIINFLAMMATORY, DIURETIC, ANESTHETIC OR NEUROPROTECTIVE AGENTS | PFIZER INC. (US) | 2000-08-29 | — | — | US | disclosed |
| US-5952369-A | ANALGESIC, TREATMENT FOR STROKE OR ABDOMINAL PAIN ASSOCIATED WITH FUNCTIONAL BOWEL DISEASE | PFIZER INC (US) | 1999-09-14 | — | — | US | disclosed |
| WO-1996030339-A1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER INC. (US) | 1996-10-03 | — | — | WO | disclosed |