Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.62 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | HTT | P42858 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8983488 | 0.98 | ALDH1A1 (0.64) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL6981800 | 0.97 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL6301912 | 0.83 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL14633632 | 0.83 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL6162468 | 0.81 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL8983560 | 0.81 | KMT2A (0.68) | ALDH1A1SMN1; SMN2MAPTHTTALOX12 | |
| SCHEMBL6297678 | 0.78 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL458335 | 0.77 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL4050791 | 0.77 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2MAPTLMNAHTT | |
| SCHEMBL5078630 | 0.77 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228058-B1 | BENZOPYRANYL GUANIDINE DERIVATIVES, PROCESS FOR PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DONGBU HANNONG CHEMICAL CO LTD (KR) | 2003-12-10 | — | — | EP | disclosed |
| US-6323238-B1 | CARDIOVASCULAR DISORDERS, NERVOUS SYSTEM DISORDERS | DONGBU HANNONG CHEMICAL CO., LTD. (KR) | 2001-11-27 | — | — | US | disclosed |