Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985858 | 0.80 | HTT (0.38) | HTTGAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL7682179 | 0.74 | HTT (0.40) | HTTGAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL6980776 | 0.74 | HTT (0.40) | HTTGAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL8143426 | 0.70 | HTT (0.40) | HTTGAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL3843668 | 0.70 | HTT (0.40) | HTTGAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL3843016 | 0.68 | HTT (0.39) | HTTGAAMEN1KMT2AL3MBTL1 | |
| SCHEMBL9070627 | 0.67 | GAA (0.48) | GAAMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL10709995 | 0.62 | SMN1; SMN2 (0.44) | GAAMEN1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL14661745 | 0.62 | POLB (0.52) | GAAPOLBGFER | |
| SCHEMBL6987389 | 0.62 | ELANE (0.42) | HTTGAAMEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |