Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987576 | 0.87 | TSHR (0.43) | KDM4EALDH1A1MAPTTSHRHSD17B10 | |
| SCHEMBL6704355 | 0.73 | ACHE (0.44) | ELANEKDM4EALDH1A1MAPTTSHR | |
| SCHEMBL6987698 | 0.72 | NPSR1 (0.45) | ELANEKDM4EALDH1A1HSD17B10PDE4A | |
| SCHEMBL6703008 | 0.71 | ALDH1A1 (0.41) | ELANEKDM4EALDH1A1MAPTTSHR | |
| SCHEMBL8152251 | 0.68 | TAAR1 (0.50) | ELANEKDM4ETDP1MEN1KMT2A | |
| SCHEMBL27188344 | 0.66 | TAAR1 (0.50) | TAAR1 | |
| SCHEMBL5325670 | 0.66 | TAAR1 (0.50) | KDM4EALDH1A1MAPTHSD17B10TDP1 | |
| SCHEMBL10683365 | 0.66 | TAAR1 (0.50) | KDM4EALDH1A1MAPTHSD17B10TDP1 | |
| SCHEMBL2479796 | 0.65 | ALDH1A1 (0.43) | ELANEKDM4EALDH1A1MAPTTSHR | |
| SCHEMBL2479798 | 0.65 | ALDH1A1 (0.43) | ELANEKDM4EALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |