Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682179 | 1.00 | HTT (0.40) | HTTGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6985858 | 0.82 | HTT (0.38) | HTTGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3843668 | 0.81 | HTT (0.40) | HTTGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8143426 | 0.81 | HTT (0.40) | HTTGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3843016 | 0.79 | HTT (0.39) | HTTGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3849973 | 0.76 | HTT (0.34) | HTTGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6981945 | 0.74 | HTT (0.40) | HTTGAAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6987350 | 0.69 | MEN1 (0.45) | HTTMEN1KMT2AL3MBTL1TSHR | |
| SCHEMBL8140543 | 0.64 | KDM4E (0.43) | HTTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL24467293 | 0.64 | TAAR1 (0.47) | GAAMEN1KMT2ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |