Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.73 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.57 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.52 |
| ▸ | QPCT | Q16769 | 2/20 | 0.52 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11758479 | 0.92 | CYP19A1 (0.77) | CYP19A1TBXAS1QPCT | |
| SCHEMBL11637474 | 0.89 | TBXAS1 (0.71) | CYP19A1TBXAS1QPCT | |
| SCHEMBL11636280 | 0.89 | TBXAS1 (0.71) | CYP19A1TBXAS1QPCT | |
| SCHEMBL11363968 | 0.89 | CYP19A1 (0.58) | CYP19A1TBXAS1QPCTCYP11B1CYP11B2 | |
| SCHEMBL11386158 | 0.87 | CYP19A1 (0.57) | CYP19A1TBXAS1 | |
| SCHEMBL11147343 | 0.87 | CYP19A1 (0.57) | CYP19A1TBXAS1 | |
| SCHEMBL5303970 | 0.85 | CYP19A1 (1.00) | CYP19A1TBXAS1HMOX2QPCTCYP11B1 | |
| SCHEMBL11630824 | 0.84 | CYP19A1 (0.53) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11633201 | 0.84 | CYP19A1 (0.73) | CYP19A1QPCTCYP11B1CYP11B2 | |
| SCHEMBL11756428 | 0.84 | CYP19A1 (0.53) | CYP19A1QPCTCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030199530-A1 | New compounds derived from quinazoline | LES LABORATORIES SERVIER (FR) | 2003-10-23 | — | — | US | disclosed |
| CN-1445226-A | New cornpound derivated from quinazoline, itd preparation method and medicinal composite containig them | ADIR (FR) | 2003-10-01 | — | — | CN | disclosed |
| EP-1346992-A1 | Quinazoline derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2003-09-24 | — | — | EP | disclosed |
| US-4518607-A | FUNGICIDES, BACXTERICIDES AND ANTIPROTOZOA AGENTS | SYNTEX (U.S.A.) INC. (US) | 1985-05-21 | — | — | US | disclosed |
| US-4078071-A | FUNGICIDES, BACTERICIDES, ANTIPROTOZOA AGENTS | SYNTEX (U.S.A.) INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4045568-A | FUNGICIDES, BACTERICIDES, ANTIPROTOZOA AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030199530-A1 | New compounds derived from quinazoline | NQO2, XDH, DRD1 | CYP19A1 1823/4885TBXAS1 423/4885HMOX2 3336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.