Sugi Predict

Sugi Predict / Compounds / SCHEMBL698199

SCHEMBL698199

SCHEMBL698199

O=C1OCc2c(Br)cccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PIM1 P11309 1/20 0.48
▸ CSNK1A1 P48729 1/20 0.48
▸ CDK5 Q00535 1/20 0.48
▸ ROCK1 Q13464 1/20 0.48
▸ DYRK1A Q13627 1/20 0.48
▸ LRRK2 Q5S007 1/20 0.48
▸ CLK4 Q9HAZ1 1/20 0.48
▸ DYRK1B Q9Y463 1/20 0.48
▸ KCNJ1 P48048 8/20 0.47
▸ MAOB P27338 2/20 0.47
▸ MAOA P21397 1/20 0.47
▸ PARP10 Q53GL7 1/20 0.46
▸ PARP11 Q9NR21 1/20 0.46
▸ KDM4E B2RXH2 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ TYMS P04818 1/20 0.44
▸ CYP1A2 P05177 1/20 0.44
▸ HPGD P15428 1/20 0.44
▸ CYP2C19 P33261 1/20 0.44
▸ HSD17B10 Q99714 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17128311 0.80 PARP10 (0.51) PIM1CSNK1A1CDK5ROCK1DYRK1A
SCHEMBL855079 0.78 KCNJ1 (0.46) KCNJ1MAOBMAOAKDM4EALDH1A1
SCHEMBL30991499 0.75 MAOB (0.47) KCNJ1MAOBMAOAKDM4EALDH1A1
SCHEMBL2045834 0.75 MAOB (0.47) KCNJ1MAOBMAOAKDM4EALDH1A1
SCHEMBL32672785 0.75 MAOB (0.47) KCNJ1MAOBMAOAKDM4EALDH1A1
SCHEMBL87504 0.75 MAOB (0.47) PIM1KCNJ1MAOBMAOAKDM4E
SCHEMBL7639394 0.75 KCNJ1 (0.51) PIM1KCNJ1MAOBMAOAPARP10
SCHEMBL856025 0.75 MAOB (0.47) KCNJ1MAOBMAOAKDM4EALDH1A1
SCHEMBL78594 0.75 MAOB (0.47) PIM1KCNJ1MAOBMAOAKDM4E
SCHEMBL29504833 0.75 MAOB (0.47) PIM1KCNJ1MAOBMAOAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026086928-A1 SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd. (KY) 2026-04-30 — — WO disclosed
EP-4335512-A2 CHROMENOPYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS HiberCell, Inc. (US) 2024-03-13 — — EP disclosed
EP-3728217-B1 CHROMENOPYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS HIBERCELL INC (US) 2023-11-15 — — EP disclosed
US-11584763-B2 Chromenopyridine derivatives as phosphatidylinositol phosphate kinase inhibitors HIBERCELL, INC. (US) 2023-02-21 — — US disclosed
US-11535635-B2 — — 2022-12-27 — — US disclosed
EP-3649119-B1 NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS GALAPAGOS NV (BE) 2021-11-03 — — EP disclosed
US-20210315893-A1 NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS GILEAD SCIENCES, INC. 2021-10-14 — — US disclosed
US-20210253600-A1 CHROMENOPYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS HIBERCELL, INC. 2021-08-19 — — US disclosed
CN-111936484-A Chromenopyridine derivatives as inhibitors of phosphatidylinositol phosphokinase 拉文纳制药公司 2020-11-13 — — CN disclosed
EP-3728217-A1 CHROMENOPYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS Ravenna Pharmaceuticals, Inc. (US) 2020-10-28 — — EP disclosed
US-20090312326-A1 SUBSTITUTED IMIDAZOLES PFIZER LIMITED (GB) 2009-12-17 — — US disclosed
US-7592362-B2 Substituted imidazoles PFIZER LIMITED (GB) 2009-09-22 — — US disclosed
US-7547718-B2 Substituted imidazoles PFIZER LIMITED (GB) 2009-06-16 — — US disclosed
US-7544706-B2 Substituted imidazoles PFIZER LIMITED (GB) 2009-06-09 — — US disclosed
EP-1981853-A1 SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES Pfizer Limited (GB) 2008-10-22 — — EP disclosed
US-20080125473-A1 SUBSTITUTED IMIDAZOLES PFIZER LIMITED (GB) 2008-05-29 — — US disclosed
US-20080119536-A1 SUBSTITUTED IMIDAZOLES PFIZER LIMITED (GB) 2008-05-22 — — US disclosed
WO-2007147829-A1 AZOLOPYRIMIDINE COMPOUNDS AND THEIR USE FOR CONTROLLING HARMFUL FUNGI BASF SE (DE) 2007-12-27 — — WO disclosed
WO-2007083207-A1 SUBSTITUTED IMIDAZOLES AND THEIR USE AS PESTICIDES PFIZER LIMITED (GB) 2007-07-26 — — WO disclosed
US-20070167506-A1 SUBSTITUTED IMIDAZOLES PFIZER INC. (US) 2007-07-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080125473-A1 SUBSTITUTED IMIDAZOLES ABL1, TYR, CYP3A4 PIM1 470/4885CSNK1A1 1968/4885CDK5 3150/4885
US-20090312326-A1 SUBSTITUTED IMIDAZOLES ABL1, TYR, CYP3A4 PIM1 470/4885CSNK1A1 1968/4885CDK5 3150/4885
US-20070167506-A1 SUBSTITUTED IMIDAZOLES ABL1, TYR, CYP3A4 PIM1 470/4885CSNK1A1 1968/4885CDK5 3150/4885
US-11584763-B2 Chromenopyridine derivatives as phosphatidylinositol phosphate kinase inhibitors PIP5K1A, PIP5K1B, PI4KA PIM1 680/4885CSNK1A1 247/4885CDK5 42/4885
US-20080119536-A1 SUBSTITUTED IMIDAZOLES ABL1, TYR, CYP3A4 PIM1 470/4885CSNK1A1 1968/4885CDK5 3150/4885
US-11535635-B2 — PIP5K1A, PI4K2A, PIP5K1B PIM1 1813/4885CSNK1A1 897/4885CDK5 22/4885
US-20210253600-A1 CHROMENOPYRIDINE DERIVATIVES AS PHOSPHATIDYLINOSITOL PHOSPHATE KINASE INHIBITORS PIP5K1A, PIP5K1B, PI4KA PIM1 680/4885CSNK1A1 247/4885CDK5 42/4885
US-20210315893-A1 NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS S1PR1, S1PR3, S1PR2 PIM1 3324/4885CSNK1A1 1985/4885CDK5 2538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.