Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TYMS | P04818 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | PRF1 | P14222 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30991499 | 1.00 | MAOB (0.47) | MAOBMAOAPARP1ALDH1A1LMNA | |
| Toluene SCHEMBL27962797 | 0.88 | KCNJ1 (0.43) | MAOBMAOAPARP1ALDH1A1LMNA | |
| SCHEMBL4141000 | 0.80 | PARP1 (0.51) | MAOBMAOAPARP1ALDH1A1LMNA | |
| SCHEMBL29568743 | 0.75 | KCNJ1 (0.51) | MAOBMAOAPARP1ALDH1A1LMNA | |
| SCHEMBL78594 | 0.75 | MAOB (0.47) | MAOBMAOAPARP1ALDH1A1LMNA | |
| SCHEMBL87504 | 0.75 | MAOB (0.47) | MAOBMAOAALDH1A1LMNAGAA | |
| SCHEMBL29504833 | 0.75 | MAOB (0.47) | MAOBMAOAALDH1A1LMNAGAA | |
| SCHEMBL856025 | 0.75 | MAOB (0.47) | MAOBMAOAALDH1A1LMNAGAA | |
| SCHEMBL7639394 | 0.75 | KCNJ1 (0.51) | MAOBMAOAPARP1ALDH1A1LMNA | |
| SCHEMBL698199 | 0.75 | PIM1 (0.48) | MAOBMAOAALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118420576-A | Amino acid-like guided phthalide analogues and uses thereof | 河南农业大学 | 2024-08-02 | — | — | CN | claimed |
| CN-117285491-A | Amino acid-like guided phthalide analogues and uses thereof | 河南农业大学 | 2023-12-26 | — | — | CN | claimed |
| CN-118420576-A | Amino acid-like guided phthalide analogues and uses thereof | 河南农业大学 | 2024-08-02 | — | — | CN | disclosed |
| CN-117285491-A | Amino acid-like guided phthalide analogues and uses thereof | 河南农业大学 | 2023-12-26 | — | — | CN | disclosed |
| CN-115403959-A | Preparation method of colorful resin coating stock solution with polarity difference | 扬州市祥华新材料科技有限公司 | 2022-11-29 | — | — | CN | disclosed |
| US-11364241-B2 | Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP) | MEDIVATION TECHNOLOGIES LLC (US) | 2022-06-21 | — | — | US | disclosed |
| US-20210069191-A1 | DIHYDROPYRIDOPHTHALAZINONE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | MEDIVATION TECHNOLOGIES LLC | 2021-03-11 | — | — | US | disclosed |
| US-10780088-B2 | Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP) | MEDIVATION TECHNOLOGIES LLC (US) | 2020-09-22 | — | — | US | disclosed |
| US-20200261454-A1 | DIHYDROPYRIDOPHTHALAZINONE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | MEDIVATION TECHNOLOGIES LLC | 2020-08-20 | — | — | US | disclosed |
| US-10543209-B2 | Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP) | MEDIVATION TECHNOLOGIES LLC (US) | 2020-01-28 | — | — | US | disclosed |
| US-20190070189-A1 | DIHYDROPYRIDOPHTHALAZINONE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) FOR USE IN TREATMENT OF DISEASES ASSOCIATED WITH A PTEN DEFICIENCY | BIOMARIN PHARMACEUTICAL INC. | 2019-03-07 | — | — | US | disclosed |
| EP-1670458-A1 | 1-AMINO-2-OXY-SUBSTITUTED TETRAHYDRONAPHTALENE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, AND THEIR USE AS ANTIPHLOGISTICS | SCHERING AKTIENGESELLSCHAFT (DE) | 2006-06-21 | — | — | EP | disclosed |
| US-20050272823-A1 | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-12-08 | — | — | US | disclosed |
| US-6960468-B2 | Preparing a hydrophobic copolymer in a solvent to obtain a solution of hydrophobic copolymer; coating solution of hydrophobic copolymer onto a substrate; removing solvent | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2005-11-01 | — | — | US | disclosed |
| US-20050209324-A1 | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-09-22 | — | — | US | disclosed |
| US-20050171109-A1 | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-08-04 | — | — | US | disclosed |
| WO-2005034939-A1 | 1-AMINO-2-OXY-SUBSTITUTED TETRAHYDRONAPHTALENE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF, AND THEIR USE AS ANTIPHLOGISTICS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-04-21 | — | — | WO | disclosed |
| US-20040062854-A1 | On-spot Hydrophilic enhanced slide and preparation thereof | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2004-04-01 | — | — | US | disclosed |
| US-20020122875-A1 | On-spot hydrophilic enhanced slide and preparation thereof | JAN BOR-IUAN (TW) | 2002-09-05 | — | — | US | disclosed |
| US-6403368-B1 | MALEIMIDE-STYRENE COPOLYMER | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2002-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040062854-A1 | On-spot Hydrophilic enhanced slide and preparation thereof | STUB1, PCNA, MKI67 | MAOB 1583/4885MAOA 2012/4885PARP1 4347/4885 |
| US-10780088-B2 | Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP) | PARP1, PARP2, PARP11 | MAOB 417/4885MAOA 598/4885PARP1 1/4885 |
| US-20190070189-A1 | DIHYDROPYRIDOPHTHALAZINONE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) FOR USE IN TREATMENT OF DISEASES ASSOCIATED WITH A PTEN DEFICIENCY | PARP1, PARP2, PARP11 | MAOB 574/4885MAOA 850/4885PARP1 1/4885 |
| US-11364241-B2 | Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP) | PARP1, PARP2, PARP11 | MAOB 417/4885MAOA 598/4885PARP1 1/4885 |
| US-10543209-B2 | Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP) | PARP1, PARP2, PARP11 | MAOB 417/4885MAOA 598/4885PARP1 1/4885 |
| US-20050171109-A1 | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | TNF, DHPS, PTGES | MAOB 1704/4885MAOA 1649/4885PARP1 1092/4885 |
| US-20050272823-A1 | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | DHPS, TNF, PTGES | MAOB 1097/4885MAOA 1127/4885PARP1 1048/4885 |
| US-20050209324-A1 | Tetrahydronaphthalene derivatives, process for their production and their use as anti-inflammatory agents | TNF, DHPS, PTGES | MAOB 1704/4885MAOA 1649/4885PARP1 1092/4885 |
| US-20200261454-A1 | DIHYDROPYRIDOPHTHALAZINONE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | PARP1, PARP2, PARP11 | MAOB 417/4885MAOA 598/4885PARP1 1/4885 |
| US-20210069191-A1 | DIHYDROPYRIDOPHTHALAZINONE INHIBITORS OF POLY(ADP-RIBOSE)POLYMERASE (PARP) | PARP1, PARP2, PARP11 | MAOB 417/4885MAOA 598/4885PARP1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.