SCHEMBL87504

SCHEMBL87504

O=C1OCc2c(Cl)cccc21

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.47
MAOA P21397 2/20 0.47
KDM4E B2RXH2 2/20 0.44
TYMS P04818 2/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP1A2 P05177 1/20 0.44
HPGD P15428 1/20 0.44
CYP2C19 P33261 1/20 0.44
HSD17B10 Q99714 1/20 0.44
KCNJ1 P48048 3/20 0.43
MAPT P10636 2/20 0.38
PDE4D Q08499 1/20 0.37
KCNH2 Q12809 2/20 0.37
NSD2 O96028 1/20 0.37
BCHE P06276 1/20 0.37
DAO P14920 1/20 0.37
CES1 P23141 1/20 0.37
GAA P10253 2/20 0.37
GLA P06280 1/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29504833 1.00 MAOB (0.47) MAOBMAOAKDM4ETYMSALDH1A1
SCHEMBL854575 0.78 KCNJ1 (0.46) MAOBMAOAKDM4ETYMSALDH1A1
SCHEMBL15546074 0.76 MAPT (0.40) MAOBMAOATYMSALDH1A1HSD17B10
SCHEMBL32672785 0.75 MAOB (0.47) MAOBMAOAKDM4ETYMSALDH1A1
SCHEMBL78594 0.75 MAOB (0.47) MAOBMAOAKDM4ETYMSALDH1A1
SCHEMBL30991499 0.75 MAOB (0.47) MAOBMAOAKDM4ETYMSALDH1A1
SCHEMBL856025 0.75 MAOB (0.47) MAOBMAOAKDM4ETYMSALDH1A1
SCHEMBL698199 0.75 PIM1 (0.48) MAOBMAOAKDM4ETYMSALDH1A1
SCHEMBL2045834 0.75 MAOB (0.47) MAOBMAOAKDM4ETYMSALDH1A1
SCHEMBL7639394 0.75 KCNJ1 (0.51) MAOBMAOAKDM4ETYMSALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136797-A Full continuous flow preparation method of quizalofop-p-ethyl 浙江工业大学 2025-06-13 CN claimed
CN-114755316-B Method for screening dangerous substances in food contact material and application 广州质量监督检测研究院 2024-02-27 CN claimed
US-20260116879-A1 AZAINDOLE ROCK INHIBITORS AVICENNA BIOSCIENCES, INC. (US) 2026-04-30 US disclosed
US-20260035381-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF SUMITOMO PHARMA AMERICA, INC. (US) 2026-02-05 US disclosed
EP-4642764-A2 AZAINDOLE ROCK INHIBITORS Avicenna Biosciences, Inc. (US) 2025-11-05 EP disclosed
US-12415805-B2 Azaindole rock inhibitors AVICENNA BIOSCIENCES, INC. (US) 2025-09-16 US disclosed
US-20250250273-A1 AZAINDOLE ROCK INHIBITORS AVICENNA BIOSCIENCES, INC. (US) 2025-08-07 US disclosed
US-12286433-B1 Azaindole rock inhibitors AVICENNA BIOSCIENCES, INC. (US) 2025-04-29 US disclosed
US-12281115-B2 Azaindole rock inhibitors AVICENNA BIOSCIENCES, INC. (US) 2025-04-22 US disclosed
US-20250115605-A1 AZAINDOLE ROCK INHIBITORS AVICENNA BIOSCIENCES, INC. (US) 2025-04-10 US disclosed
US-20250092038-A1 AZAINDOLE ROCK INHIBITORS AVICENNA BIOSCIENCES, INC. (US) 2025-03-20 US disclosed
US-7541489-B2 Method of making halophthalic acids and halophthalic anhydrides SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-06-02 US disclosed
US-20080275211-A1 METHOD OF MAKING HALOPHTHALIC ACIDS AND HALOPHTHALIC ANHYDRIDES SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2008-11-06 US disclosed
EP-1773747-A1 METHOD OF MAKING HALOPHTHALIC ACIDS AND HALOPHTHALIC ANHYDRIDES General Electric Company (US) 2007-04-18 EP disclosed
WO-2006004822-A1 METHOD OF MAKING HALOPHTHALIC ACIDS AND HALOPHTHALIC ANHYDRIDES GENERAL ELECTRIC COMPANY (US) 2006-01-12 WO disclosed
US-20060004224-A1 Method of making halophthalic acids and halophthalic anhydrides GENERAL ELECTRIC COMPANY 2006-01-05 US disclosed
US-20060004223-A1 Method of making halophthalic acids and halophthalic anhydrides GENERAL ELECTRIC COMPANY 2006-01-05 US disclosed
EP-1375468-A2 Method for removing impurities from oxidation products GENERAL ELECTRIC COMPANY (US) 2004-01-02 EP disclosed
US-6670487-B1 Of ortho-dimethylbenzene compounds; phthalic acid and phthalic anhydride by oxidation of ortho-xylene; extracting solution of aromatic anhydride product with an aqueous bicarbonate to hydrolyze the anhydride to the acid GENERAL ELECTRIC COMPANY 2003-12-30 US disclosed
US-4244966-A 1,3-Dihydro-3-(2-hydroxy-, 2-bromo- or 2-chloroethyl)-2H-isoindol-1-one derivatives AMERICAN HOME PRODUCTS CORPORATION (US) 1981-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12415805-B2 Azaindole rock inhibitors ROCK2, ROCK1, ARHGDIA MAOB 2468/4885MAOA 2497/4885KDM4E 494/4885
US-20060004223-A1 Method of making halophthalic acids and halophthalic anhydrides HAO2, HPD, HAAO MAOB 488/4885MAOA 533/4885KDM4E 3423/4885
US-20260035381-A1 COMPOUNDS AND COMPOSITIONS AND USES THEREOF ADH1C, HTR6, CNR1 MAOB 37/4885MAOA 57/4885KDM4E 2475/4885
US-20250250273-A1 AZAINDOLE ROCK INHIBITORS ROCK2, ROCK1, ARHGDIA MAOB 2468/4885MAOA 2497/4885KDM4E 494/4885
US-12281115-B2 Azaindole rock inhibitors ROCK2, ROCK1, ARHGDIA MAOB 2468/4885MAOA 2497/4885KDM4E 494/4885
US-20260116879-A1 AZAINDOLE ROCK INHIBITORS PRKG2, PRKG1, ROCK2 MAOB 1428/4885MAOA 875/4885KDM4E 637/4885
US-20250115605-A1 AZAINDOLE ROCK INHIBITORS ROCK2, ROCK1, ARHGDIA MAOB 2468/4885MAOA 2497/4885KDM4E 494/4885
US-20060004224-A1 Method of making halophthalic acids and halophthalic anhydrides HAO2, HPD, HAAO MAOB 525/4885MAOA 627/4885KDM4E 3171/4885
US-12286433-B1 Azaindole rock inhibitors ROCK2, ROCK1, ARHGDIA MAOB 2468/4885MAOA 2497/4885KDM4E 494/4885
US-20080275211-A1 METHOD OF MAKING HALOPHTHALIC ACIDS AND HALOPHTHALIC ANHYDRIDES HAO2, HPD, HAAO MAOB 525/4885MAOA 627/4885KDM4E 3171/4885
US-20250092038-A1 AZAINDOLE ROCK INHIBITORS ROCK2, ROCK1, ARHGDIA MAOB 2468/4885MAOA 2497/4885KDM4E 494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.