SCHEMBL698212

SCHEMBL698212

Nc1ccc(SC(F)(F)C(F)(F)C(F)(F)F)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
TDP1 Q9NUW8 2/20 0.61
KDM4E B2RXH2 1/20 0.61
KMT2A Q03164 4/20 0.44
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.44
CYP3A4 P08684 2/20 0.42
TSHR P16473 2/20 0.42
MAPK1 P28482 1/20 0.42
KIF11 P52732 1/20 0.35
MEN1 O00255 3/20 0.35
MAPT P10636 2/20 0.35
APP P05067 1/20 0.32
PTPN1 P18031 1/20 0.31
PTPRZ1 P23471 1/20 0.31
PDE7A Q13946 2/20 0.31
TP53 P04637 1/20 0.31
GLA P06280 1/20 0.30
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9187691 0.92 ALDH1A1 (0.57) ALDH1A1TDP1KDM4EKMT2ALMNA
SCHEMBL8639823 0.86 ALDH1A1 (0.67) ALDH1A1TDP1KDM4EKMT2ALMNA
SCHEMBL25118394 0.78 ALDH1A1 (0.61) ALDH1A1TDP1KDM4EKMT2ACYP3A4
SCHEMBL776220 0.77 ALDH1A1 (0.46) ALDH1A1TDP1KDM4EKMT2ALMNA
SCHEMBL656930 0.77 ALDH1A1 (1.00) ALDH1A1TDP1KDM4EKMT2ALMNA
SCHEMBL1359660 0.76 TSHR (0.42) ALDH1A1TDP1KDM4EKMT2ALMNA
SCHEMBL4145466 0.75 ALDH1A1 (0.41) ALDH1A1TDP1KDM4EKMT2ALMNA
SCHEMBL11298765 0.75 ALDH1A1 (0.70) ALDH1A1TDP1KDM4EKMT2ATHRB
SCHEMBL698851 0.74 ALDH1A1 (0.41) ALDH1A1TDP1KDM4EKMT2ALMNA
SCHEMBL698093 0.74 LMNA (0.35) ALDH1A1TDP1KDM4EKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230373947-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE MITSUI CHEMICALS, INC. (JP) 2023-11-23 US disclosed
US-11760742-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2023-09-19 US disclosed
US-20210230135-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE MITSUI CHEMICALS, INC. (JP) 2021-07-29 US disclosed
US-10995081-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2021-05-04 US disclosed
EP-2423188-B1 Intermediates in the preparation of agricultural/horticultural insecticides and method for using the same MITSUI CHEMICALS AGRO INC (JP) 2021-03-10 EP disclosed
US-10435385-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2019-10-08 US disclosed
US-20180134681-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE MITSUI CHEMICALS, INC. (JP) 2018-05-17 US disclosed
US-9920026-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide MITSUI CHEMICALS, INC. (JP) 2018-03-20 US disclosed
EP-1714958-B9 AMIDE DERIVATIVES, PROCESS FOR PRODUCTION OF THE SAME, AND METHOD FOR APPLICATION THEREOF AS INSECTICIDE MITSUI CHEMICALS AGRO INC (JP) 2017-05-31 EP disclosed
EP-1714958-B1 AMIDE DERIVATIVES, PROCESS FOR PRODUCTION OF THE SAME, AND METHOD FOR APPLICATION THEREOF AS INSECTICIDE MITSUI CHEMICALS AGRO INC (JP) 2016-12-21 EP disclosed
EP-1938685-A1 INSECTICIDAL AND BACTERICIDAL COMPOSITION Mitsui Chemicals, Inc. (JP) 2008-07-02 EP disclosed
EP-1913815-A1 PEST CONTROL COMPOSITION Mitsui Chemicals, Inc. (JP) 2008-04-23 EP disclosed
US-20070275980-A1 Amide Derivatives, Process For Preparation Thereof And Use Thereof As Insecticide MITSUI CHEMICALS, INC. (JP) 2007-11-29 US disclosed
US-20070027154-A1 Insecticide for agricultural or horticultural use and method of use thereof MITSUI CHEMICALS., INC. (JP) 2007-02-01 US disclosed
EP-1714958-A1 AMIDE DERIVATIVES, PROCESS FOR PRODUCTION OF THE SAME, AND METHOD FOR APPLICATION THEREOF AS INSECTICIDE Mitsui Chemicals, Inc. (JP) 2006-10-25 EP disclosed
EP-1661886-A1 INSECTICIDE FOR AGRICULTURAL OR HORTICULTURAL USE AND METHOD OF USE THEREOF Mitsui Chemicals, Inc. (JP) 2006-05-31 EP disclosed
EP-0572973-B1 Metal chelate compound and optical recording medium using the compound MITSUBISHI CHEM CORP (JP) 1998-08-19 EP disclosed
US-5532342-A Azo metal chelate compound MITSUBISHI CHEMICAL CORPORATION (JP) 1996-07-02 US disclosed
US-5447823-A Metal chelate compound and optical recording medium using the compound MITSUBISHI CHEMICAL CORPORATION (JP) 1995-09-05 US disclosed
EP-0572973-A2 Metal chelate compound and optical recording medium using the compound Mitsubishi Chemical Corporation (JP) 1993-12-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070275980-A1 Amide Derivatives, Process For Preparation Thereof And Use Thereof As Insecticide CYP1A1, CYP4B1, CYP2E1 ALDH1A1 238/4885TDP1 3121/4885KDM4E 2293/4885
US-20180134681-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE CYP1A1, CYP4B1, CYP2E1 ALDH1A1 238/4885TDP1 3121/4885KDM4E 2293/4885
US-20070027154-A1 Insecticide for agricultural or horticultural use and method of use thereof CBR3, ATL3, CNPY2 ALDH1A1 1149/4885TDP1 2054/4885KDM4E 2070/4885
US-20230373947-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE DDT, CYP4B1, CYP2E1 ALDH1A1 103/4885TDP1 3316/4885KDM4E 335/4885
US-20210230135-A1 AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE DDT, CYP4B1, CYP2E1 ALDH1A1 103/4885TDP1 3316/4885KDM4E 335/4885
US-10435385-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide DDT, CYP4B1, CYP2E1 ALDH1A1 103/4885TDP1 3316/4885KDM4E 335/4885
US-11760742-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide DDT, CYP4B1, CYP2E1 ALDH1A1 103/4885TDP1 3316/4885KDM4E 335/4885
US-10995081-B2 Amide derivatives, process for preparation thereof and use thereof as insecticide DDT, CYP4B1, CYP2E1 ALDH1A1 103/4885TDP1 3316/4885KDM4E 335/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.