Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCB | P05771 | 7/20 | 0.51 |
| ▸ | PRKCA | P17252 | 7/20 | 0.51 |
| ▸ | PRKCE | Q02156 | 7/20 | 0.51 |
| ▸ | PRKD3 | O94806 | 6/20 | 0.51 |
| ▸ | PRKCG | P05129 | 6/20 | 0.51 |
| ▸ | PRKCH | P24723 | 6/20 | 0.51 |
| ▸ | PRKCI | P41743 | 6/20 | 0.51 |
| ▸ | PRKCQ | Q04759 | 6/20 | 0.51 |
| ▸ | PRKCZ | Q05513 | 6/20 | 0.51 |
| ▸ | PRKCD | Q05655 | 6/20 | 0.51 |
| ▸ | PRKD1 | Q15139 | 6/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | RECQL | P46063 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6984632 | 0.94 | PRKCB (0.46) | PRKCBPRKCAPRKCEPRKD3PRKCG | |
| SCHEMBL6979903 | 0.88 | CCNT1 (0.45) | PRKCBPRKCAPRKCEPRKD3PRKCG | |
| SCHEMBL6976742 | 0.87 | PRKACA (0.43) | PRKCBPRKCAPRKCEPRKD3PRKCG | |
| SCHEMBL6981937 | 0.86 | CAMK2D (0.56) | PRKCBPRKCAPRKCEPRKD3PRKCG | |
| SCHEMBL6982388 | 0.86 | PRKACA (0.56) | PRKCBPRKCAPRKCEPRKD3PRKCG | |
| SCHEMBL6979319 | 0.85 | CAMK2D (0.52) | PRKCBPRKCAPRKCEPRKD3PRKCG | |
| SCHEMBL7005333 | 0.85 | PRKCB (0.56) | PRKCBPRKCAPRKCEPRKD3PRKCG | |
| SCHEMBL6980064 | 0.85 | PRKACA (0.52) | PRKCBPRKCAPRKCEPRKD3PRKCG | |
| SCHEMBL7835441 | 0.84 | PRKACA (0.44) | PRKCBPRKCAPRKCEPRKD3PRKCG | |
| Trifluoroacetic Acid SCHEMBL6982571 | 0.83 | CCNT1 (0.44) | PRKCBPRKCAPRKCEPRKD3PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095039-B1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-08-27 | — | — | EP | claimed |
| US-6346625-B1 | ENZYME INHIBITORS FOR PROTEIN KINASES | ASTRAZENECA AB (SE) | 2002-02-12 | — | — | US | claimed |
| EP-1095039-B1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-08-27 | — | — | EP | disclosed |
| US-6346625-B1 | ENZYME INHIBITORS FOR PROTEIN KINASES | ASTRAZENECA AB (SE) | 2002-02-12 | — | — | US | disclosed |